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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PRPF39 All Species: 11.82
Human Site: T297 Identified Species: 26
UniProt: Q86UA1 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UA1 NP_060392.3 669 78430 T297 P S G I E D I T D P A K L I T
Chimpanzee Pan troglodytes XP_001151081 664 77842 T292 P S G I E D I T D P A K L I T
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_851059 548 64272 P220 F E E G I K R P Y F H V K P L
Cat Felis silvestris
Mouse Mus musculus Q8K2Z2 665 77903 S295 P S G I E D I S P A K L I T E
Rat Rattus norvegicus NP_001101496 299 34936
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001514648 669 78057 T297 P S G I E D I T D P A K L I T
Chicken Gallus gallus
Frog Xenopus laevis Q4KLU2 641 74544 Q289 H R I I E V H Q E I F N L N E
Zebra Danio Brachydanio rerio Q1JPZ7 752 85928 P372 P P G T E D L P D P A K R V T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q7KRW8 1066 120527 D623 E T Q V D E S D S T T D L T T
Honey Bee Apis mellifera XP_392380 946 108879 P526 A P P G E E P P P H E L P P T
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793456 813 92707 P396 P P G E E A P P G V G P P S T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 N.A. 78.7 N.A. 93.4 41.1 N.A. 87.8 N.A. 65.4 58.7 N.A. 28.6 33 N.A. 37.1
Protein Similarity: 100 99.2 N.A. 80.8 N.A. 96.5 43.6 N.A. 93.7 N.A. 79.2 73.2 N.A. 41.5 46.8 N.A. 50.6
P-Site Identity: 100 100 N.A. 0 N.A. 46.6 0 N.A. 100 N.A. 20 60 N.A. 13.3 13.3 N.A. 26.6
P-Site Similarity: 100 100 N.A. 0 N.A. 60 0 N.A. 100 N.A. 26.6 73.3 N.A. 40 20 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 10 0 0 0 10 37 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 10 46 0 10 37 0 0 10 0 0 0 % D
% Glu: 10 10 10 10 73 19 0 0 10 0 10 0 0 0 19 % E
% Phe: 10 0 0 0 0 0 0 0 0 10 10 0 0 0 0 % F
% Gly: 0 0 55 19 0 0 0 0 10 0 10 0 0 0 0 % G
% His: 10 0 0 0 0 0 10 0 0 10 10 0 0 0 0 % H
% Ile: 0 0 10 46 10 0 37 0 0 10 0 0 10 28 0 % I
% Lys: 0 0 0 0 0 10 0 0 0 0 10 37 10 0 0 % K
% Leu: 0 0 0 0 0 0 10 0 0 0 0 19 46 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 10 0 10 0 % N
% Pro: 55 28 10 0 0 0 19 37 19 37 0 10 19 19 0 % P
% Gln: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % Q
% Arg: 0 10 0 0 0 0 10 0 0 0 0 0 10 0 0 % R
% Ser: 0 37 0 0 0 0 10 10 10 0 0 0 0 10 0 % S
% Thr: 0 10 0 10 0 0 0 28 0 10 10 0 0 19 64 % T
% Val: 0 0 0 10 0 10 0 0 0 10 0 10 0 10 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _