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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PRPF39
All Species:
3.03
Human Site:
T69
Identified Species:
6.67
UniProt:
Q86UA1
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UA1
NP_060392.3
669
78430
T69
S
A
V
D
L
P
V
T
L
T
E
T
E
A
N
Chimpanzee
Pan troglodytes
XP_001151081
664
77842
A70
V
T
L
T
E
T
E
A
N
F
P
P
E
Y
E
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_851059
548
64272
Cat
Felis silvestris
Mouse
Mus musculus
Q8K2Z2
665
77903
T69
N
A
V
N
L
P
V
T
E
A
E
G
D
F
P
Rat
Rattus norvegicus
NP_001101496
299
34936
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001514648
669
78057
P69
I
T
N
V
G
E
L
P
G
T
D
V
E
A
Q
Chicken
Gallus gallus
Frog
Xenopus laevis
Q4KLU2
641
74544
D69
S
V
Q
A
Y
P
E
D
F
N
T
W
T
Y
L
Zebra Danio
Brachydanio rerio
Q1JPZ7
752
85928
P140
E
P
A
A
E
A
D
P
A
A
P
Q
E
P
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q7KRW8
1066
120527
K353
D
K
D
K
D
N
N
K
D
K
E
K
E
R
K
Honey Bee
Apis mellifera
XP_392380
946
108879
K302
G
D
N
K
Q
E
I
K
P
A
S
P
K
K
K
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_793456
813
92707
R158
K
K
E
G
G
S
K
R
K
R
K
K
E
R
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
N.A.
78.7
N.A.
93.4
41.1
N.A.
87.8
N.A.
65.4
58.7
N.A.
28.6
33
N.A.
37.1
Protein Similarity:
100
99.2
N.A.
80.8
N.A.
96.5
43.6
N.A.
93.7
N.A.
79.2
73.2
N.A.
41.5
46.8
N.A.
50.6
P-Site Identity:
100
6.6
N.A.
0
N.A.
46.6
0
N.A.
20
N.A.
13.3
6.6
N.A.
13.3
0
N.A.
6.6
P-Site Similarity:
100
13.3
N.A.
0
N.A.
66.6
0
N.A.
33.3
N.A.
13.3
6.6
N.A.
13.3
13.3
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
19
10
19
0
10
0
10
10
28
0
0
0
19
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
10
10
10
10
10
0
10
10
10
0
10
0
10
0
0
% D
% Glu:
10
0
10
0
19
19
19
0
10
0
28
0
55
0
19
% E
% Phe:
0
0
0
0
0
0
0
0
10
10
0
0
0
10
0
% F
% Gly:
10
0
0
10
19
0
0
0
10
0
0
10
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
10
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% I
% Lys:
10
19
0
19
0
0
10
19
10
10
10
19
10
10
19
% K
% Leu:
0
0
10
0
19
0
10
0
10
0
0
0
0
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
0
19
10
0
10
10
0
10
10
0
0
0
0
10
% N
% Pro:
0
10
0
0
0
28
0
19
10
0
19
19
0
10
10
% P
% Gln:
0
0
10
0
10
0
0
0
0
0
0
10
0
0
10
% Q
% Arg:
0
0
0
0
0
0
0
10
0
10
0
0
0
19
0
% R
% Ser:
19
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% S
% Thr:
0
19
0
10
0
10
0
19
0
19
10
10
10
0
10
% T
% Val:
10
10
19
10
0
0
19
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% W
% Tyr:
0
0
0
0
10
0
0
0
0
0
0
0
0
19
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _