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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TMEM135
All Species:
39.39
Human Site:
S286
Identified Species:
72.22
UniProt:
Q86UB9
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UB9
NP_075069.2
458
52291
S286
R
H
L
F
T
Q
P
S
R
L
L
S
L
F
Y
Chimpanzee
Pan troglodytes
XP_001175336
458
52311
S286
R
H
L
F
T
Q
P
S
R
L
L
S
L
F
Y
Rhesus Macaque
Macaca mulatta
XP_001104105
458
52398
S286
R
H
L
F
T
Q
P
S
R
L
L
S
L
F
Y
Dog
Lupus familis
XP_848695
458
52312
S286
R
H
L
F
T
Q
P
S
R
L
F
S
L
F
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q9CYV5
458
52345
S286
R
H
L
F
T
E
P
S
R
L
L
S
L
F
Y
Rat
Rattus norvegicus
Q5U4F4
458
52340
S286
R
H
L
F
T
E
P
S
R
L
L
S
L
F
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512018
482
54954
S310
R
H
L
F
T
K
P
S
R
L
L
S
L
F
Y
Chicken
Gallus gallus
XP_417208
462
52692
S290
R
H
L
F
T
K
P
S
R
L
L
S
L
F
Y
Frog
Xenopus laevis
Q6GQ39
453
51938
S281
R
H
L
F
T
K
P
S
R
L
L
S
L
F
Y
Zebra Danio
Brachydanio rerio
NP_001082887
465
52617
S293
R
Q
A
F
T
K
P
S
R
L
L
W
L
L
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_649803
455
50901
M284
K
R
I
T
A
G
K
M
P
W
K
K
M
I
F
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
NP_508800
445
50447
E283
I
T
L
L
V
S
K
E
N
L
K
L
P
L
F
Sea Urchin
Strong. purpuratus
XP_788346
818
91850
G648
S
S
A
F
S
N
P
G
E
I
P
R
A
L
Y
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
99.1
95.8
N.A.
91.9
91.4
N.A.
81.1
82.4
79.6
74.6
N.A.
31.8
N.A.
32
24.3
Protein Similarity:
100
99.5
99.3
98.2
N.A.
96
95.6
N.A.
86.3
91.1
89.9
85.1
N.A.
50.4
N.A.
49.5
36.6
P-Site Identity:
100
100
100
93.3
N.A.
93.3
93.3
N.A.
93.3
93.3
93.3
66.6
N.A.
0
N.A.
13.3
20
P-Site Similarity:
100
100
100
93.3
N.A.
100
100
N.A.
100
100
100
73.3
N.A.
26.6
N.A.
20
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
16
0
8
0
0
0
0
0
0
0
8
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
16
0
8
8
0
0
0
0
0
0
% E
% Phe:
0
0
0
85
0
0
0
0
0
0
8
0
0
70
16
% F
% Gly:
0
0
0
0
0
8
0
8
0
0
0
0
0
0
0
% G
% His:
0
70
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
0
8
0
0
0
0
0
0
8
0
0
0
8
0
% I
% Lys:
8
0
0
0
0
31
16
0
0
0
16
8
0
0
0
% K
% Leu:
0
0
77
8
0
0
0
0
0
85
70
8
77
24
0
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
8
0
0
% M
% Asn:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
85
0
8
0
8
0
8
0
0
% P
% Gln:
0
8
0
0
0
31
0
0
0
0
0
0
0
0
0
% Q
% Arg:
77
8
0
0
0
0
0
0
77
0
0
8
0
0
0
% R
% Ser:
8
8
0
0
8
8
0
77
0
0
0
70
0
0
0
% S
% Thr:
0
8
0
8
77
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
8
0
8
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
85
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _