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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OAF All Species: 10.3
Human Site: S253 Identified Species: 20.61
UniProt: Q86UD1 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.45
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UD1 NP_848602.1 273 30688 S253 R S C Q K S Y S F D F Y V P Q
Chimpanzee Pan troglodytes XP_001166728 273 30599 S253 R S C Q K S Y S F D F Y V P Q
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_546479 305 34646 N286 G I R S C Q K N Y S F D F Y V
Cat Felis silvestris
Mouse Mus musculus Q8QZR4 282 31506 S263 G I R S C R K S Y T F D F Y V
Rat Rattus norvegicus Q6AYE5 282 31757 S263 G I R S C R K S Y R F D F Y V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520905 238 26580 K218 C G I R S C Q K S Y G F D Y Y
Chicken Gallus gallus Q71SY6 270 30561 K250 C G I R S C Q K G Y T F D Y Y
Frog Xenopus laevis Q6GPK2 269 31120 K249 C G I R S C Q K A F T F H F Y
Zebra Danio Brachydanio rerio XP_700455 272 31173 K252 C G I K S C S K G Y Q F T Y Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NLA6 487 53700 Q317 K T C R K C T Q F T Y Y V R Q
Honey Bee Apis mellifera XP_395978 407 46133 K388 K C G I K T C K K C F I F S Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_793899 236 26780 S209 K T C K R C H S F N Y H V D Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.9 N.A. 64.2 N.A. 84 84 N.A. 50.1 71.4 61.9 56.4 N.A. 24.2 27.2 N.A. 30.7
Protein Similarity: 100 99.6 N.A. 70.4 N.A. 89 87.9 N.A. 59.7 82.7 75.8 75.4 N.A. 34.2 42 N.A. 53.4
P-Site Identity: 100 100 N.A. 6.6 N.A. 13.3 13.3 N.A. 0 0 0 0 N.A. 40 13.3 N.A. 33.3
P-Site Similarity: 100 100 N.A. 20 N.A. 20 20 N.A. 13.3 13.3 13.3 13.3 N.A. 66.6 26.6 N.A. 86.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 0 % A
% Cys: 34 9 34 0 25 50 9 0 0 9 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 17 0 25 17 9 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 34 9 50 34 34 9 0 % F
% Gly: 25 34 9 0 0 0 0 0 17 0 9 0 0 0 0 % G
% His: 0 0 0 0 0 0 9 0 0 0 0 9 9 0 0 % H
% Ile: 0 25 34 9 0 0 0 0 0 0 0 9 0 0 0 % I
% Lys: 25 0 0 17 34 0 25 42 9 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % P
% Gln: 0 0 0 17 0 9 25 9 0 0 9 0 0 0 34 % Q
% Arg: 17 0 25 34 9 17 0 0 0 9 0 0 0 9 0 % R
% Ser: 0 17 0 25 34 17 9 42 9 9 0 0 0 9 0 % S
% Thr: 0 17 0 0 0 9 9 0 0 17 17 0 9 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 0 0 34 0 25 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 17 0 25 25 17 25 0 50 42 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _