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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NHEDC2
All Species:
18.18
Human Site:
Y486
Identified Species:
66.67
UniProt:
Q86UD5
Number Species:
6
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UD5
NP_849155.2
537
57564
Y486
G
E
K
Q
L
E
D
Y
G
M
D
V
L
T
V
Chimpanzee
Pan troglodytes
XP_517374
537
57648
Y486
G
E
K
Q
L
E
D
Y
G
M
D
V
L
T
V
Rhesus Macaque
Macaca mulatta
XP_001110438
537
57509
Y486
G
E
K
Q
L
E
D
Y
G
M
D
V
L
T
V
Dog
Lupus familis
XP_852596
537
57838
Y486
G
E
R
Q
L
E
E
Y
G
M
D
V
L
T
V
Cat
Felis silvestris
Mouse
Mus musculus
Q5BKR2
547
58944
Y486
G
E
K
Q
L
E
D
Y
G
M
D
V
L
T
V
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516421
234
24801
L196
W
K
R
A
Y
L
V
L
G
L
S
V
F
A
V
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_799202
601
64264
I515
G
S
E
E
E
L
E
I
Y
G
I
Q
L
L
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
98.5
86.9
N.A.
78.9
N.A.
N.A.
35.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
45.2
Protein Similarity:
100
99.6
99.2
93.3
N.A.
87.7
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
60.5
P-Site Identity:
100
100
100
86.6
N.A.
100
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
100
N.A.
100
N.A.
N.A.
40
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
15
0
0
0
0
0
0
0
0
0
15
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
58
0
0
0
72
0
0
0
0
% D
% Glu:
0
72
15
15
15
72
29
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
15
0
0
% F
% Gly:
86
0
0
0
0
0
0
0
86
15
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
15
0
0
15
0
0
0
0
% I
% Lys:
0
15
58
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
72
29
0
15
0
15
0
0
86
15
0
% L
% Met:
0
0
0
0
0
0
0
0
0
72
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
72
0
0
0
0
0
0
0
15
0
0
0
% Q
% Arg:
0
0
29
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
15
0
0
0
0
0
0
0
0
15
0
0
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
72
15
% T
% Val:
0
0
0
0
0
0
15
0
0
0
0
86
0
0
86
% V
% Trp:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
72
15
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _