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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLCO6A1
All Species:
9.7
Human Site:
S358
Identified Species:
26.67
UniProt:
Q86UG4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UG4
NP_775759.3
719
79232
S358
K
Q
L
H
F
F
D
S
R
L
K
D
L
K
L
Chimpanzee
Pan troglodytes
XP_517854
724
78864
S358
S
Q
A
H
Q
S
N
S
N
A
D
V
K
F
G
Rhesus Macaque
Macaca mulatta
XP_001095830
723
80180
S365
K
Q
R
H
W
F
D
S
K
L
K
D
L
Q
V
Dog
Lupus familis
XP_546002
1141
125207
L343
K
Q
P
N
P
F
K
L
K
I
K
D
Q
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGD4
722
78394
S353
S
Q
T
H
Q
N
N
S
T
S
F
Q
H
T
D
Rat
Rattus norvegicus
Q71MB6
724
78618
S353
S
Q
T
H
Q
N
N
S
T
S
F
Q
H
M
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505407
829
89024
S481
S
Q
T
H
Q
D
K
S
I
T
V
V
S
D
E
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696263
725
78339
S351
A
H
Q
L
K
D
G
S
Q
V
T
A
S
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198059
772
84602
F374
L
A
F
P
L
C
G
F
M
R
P
L
P
G
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.5
81.8
37.5
N.A.
38.9
38.6
N.A.
36.3
N.A.
N.A.
29.6
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
57.7
88.9
47.5
N.A.
57.2
57.3
N.A.
51.6
N.A.
N.A.
49.7
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
20
66.6
33.3
N.A.
20
20
N.A.
20
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
26.6
93.3
60
N.A.
26.6
26.6
N.A.
20
N.A.
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
12
12
0
0
0
0
0
0
12
0
12
0
0
12
% A
% Cys:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
23
23
0
0
0
12
34
0
23
23
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
12
% E
% Phe:
0
0
12
0
12
34
0
12
0
0
23
0
0
12
12
% F
% Gly:
0
0
0
0
0
0
23
0
0
0
0
0
0
12
12
% G
% His:
0
12
0
67
0
0
0
0
0
0
0
0
23
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
12
12
0
0
0
0
0
% I
% Lys:
34
0
0
0
12
0
23
0
23
0
34
0
12
12
0
% K
% Leu:
12
0
12
12
12
0
0
12
0
23
0
12
23
0
12
% L
% Met:
0
0
0
0
0
0
0
0
12
0
0
0
0
12
0
% M
% Asn:
0
0
0
12
0
23
34
0
12
0
0
0
0
0
0
% N
% Pro:
0
0
12
12
12
0
0
0
0
0
12
0
12
0
12
% P
% Gln:
0
78
12
0
45
0
0
0
12
0
0
23
12
12
0
% Q
% Arg:
0
0
12
0
0
0
0
0
12
12
0
0
0
0
0
% R
% Ser:
45
0
0
0
0
12
0
78
0
23
0
0
23
0
0
% S
% Thr:
0
0
34
0
0
0
0
0
23
12
12
0
0
12
0
% T
% Val:
0
0
0
0
0
0
0
0
0
12
12
23
0
0
12
% V
% Trp:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _