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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLCO6A1 All Species: 4.55
Human Site: S515 Identified Species: 12.5
UniProt: Q86UG4 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UG4 NP_775759.3 719 79232 S515 C S S S I Y S S I C G R D D I
Chimpanzee Pan troglodytes XP_517854 724 78864 P514 C S R S Y Y Y P V C G D G V Q
Rhesus Macaque Macaca mulatta XP_001095830 723 80180 S522 C S S S V Y S S I C G R D D I
Dog Lupus familis XP_546002 1141 125207 A500 C S S S F Y S A V C G R D N I
Cat Felis silvestris
Mouse Mus musculus Q8BGD4 722 78394 P513 C L R S Y Y Y P L C G S D G I
Rat Rattus norvegicus Q71MB6 724 78618 P513 C L R S Y Y Y P L C G S D G V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001505407 829 89024 C633 P C N A N C S C L R S F Y Y P
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_696263 725 78339 P512 C L E E S F N P V C G A D G V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001198059 772 84602 V558 C A N E F Q P V C G E D N V M
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 39.5 81.8 37.5 N.A. 38.9 38.6 N.A. 36.3 N.A. N.A. 29.6 N.A. N.A. N.A. N.A. 27.5
Protein Similarity: 100 57.7 88.9 47.5 N.A. 57.2 57.3 N.A. 51.6 N.A. N.A. 49.7 N.A. N.A. N.A. N.A. 47.2
P-Site Identity: 100 40 93.3 73.3 N.A. 46.6 40 N.A. 6.6 N.A. N.A. 26.6 N.A. N.A. N.A. N.A. 6.6
P-Site Similarity: 100 46.6 100 93.3 N.A. 53.3 53.3 N.A. 26.6 N.A. N.A. 53.3 N.A. N.A. N.A. N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 12 0 12 0 0 0 12 0 0 0 12 0 0 0 % A
% Cys: 89 12 0 0 0 12 0 12 12 78 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 23 67 23 0 % D
% Glu: 0 0 12 23 0 0 0 0 0 0 12 0 0 0 0 % E
% Phe: 0 0 0 0 23 12 0 0 0 0 0 12 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 12 78 0 12 34 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 12 0 0 0 23 0 0 0 0 0 45 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % K
% Leu: 0 34 0 0 0 0 0 0 34 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 12 % M
% Asn: 0 0 23 0 12 0 12 0 0 0 0 0 12 12 0 % N
% Pro: 12 0 0 0 0 0 12 45 0 0 0 0 0 0 12 % P
% Gln: 0 0 0 0 0 12 0 0 0 0 0 0 0 0 12 % Q
% Arg: 0 0 34 0 0 0 0 0 0 12 0 34 0 0 0 % R
% Ser: 0 45 34 67 12 0 45 23 0 0 12 23 0 0 0 % S
% Thr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % T
% Val: 0 0 0 0 12 0 0 12 34 0 0 0 0 23 23 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 34 67 34 0 0 0 0 0 12 12 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _