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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLCO6A1
All Species:
21.82
Human Site:
S642
Identified Species:
60
UniProt:
Q86UG4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UG4
NP_775759.3
719
79232
S642
F
K
M
S
G
E
T
S
C
I
L
R
D
V
N
Chimpanzee
Pan troglodytes
XP_517854
724
78864
T641
F
G
F
T
I
D
S
T
C
I
L
W
D
I
N
Rhesus Macaque
Macaca mulatta
XP_001095830
723
80180
S649
F
K
M
S
G
E
N
S
C
I
F
R
D
V
N
Dog
Lupus familis
XP_546002
1141
125207
S627
F
R
M
A
G
D
T
S
C
I
F
R
V
T
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGD4
722
78394
T639
F
G
V
I
I
D
S
T
C
V
L
W
D
V
N
Rat
Rattus norvegicus
Q71MB6
724
78618
T641
F
G
V
T
I
D
S
T
C
V
L
W
D
I
N
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505407
829
89024
I755
F
L
R
L
L
G
T
I
P
G
P
I
L
F
G
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696263
725
78339
S638
F
G
S
V
I
D
I
S
C
L
L
W
E
E
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198059
772
84602
S686
F
G
A
L
I
D
R
S
C
L
L
W
E
Y
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.5
81.8
37.5
N.A.
38.9
38.6
N.A.
36.3
N.A.
N.A.
29.6
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
57.7
88.9
47.5
N.A.
57.2
57.3
N.A.
51.6
N.A.
N.A.
49.7
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
40
86.6
53.3
N.A.
40
33.3
N.A.
13.3
N.A.
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
73.3
86.6
73.3
N.A.
73.3
80
N.A.
13.3
N.A.
N.A.
46.6
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
12
12
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
89
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
67
0
0
0
0
0
0
56
0
0
% D
% Glu:
0
0
0
0
0
23
0
0
0
0
0
0
23
12
12
% E
% Phe:
100
0
12
0
0
0
0
0
0
0
23
0
0
12
0
% F
% Gly:
0
56
0
0
34
12
0
0
0
12
0
0
0
0
12
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
12
56
0
12
12
0
45
0
12
0
23
0
% I
% Lys:
0
23
0
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
12
0
23
12
0
0
0
0
23
67
0
12
0
0
% L
% Met:
0
0
34
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
12
0
0
0
0
0
0
0
56
% N
% Pro:
0
0
0
0
0
0
0
0
12
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
23
% Q
% Arg:
0
12
12
0
0
0
12
0
0
0
0
34
0
0
0
% R
% Ser:
0
0
12
23
0
0
34
56
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
23
0
0
34
34
0
0
0
0
0
12
0
% T
% Val:
0
0
23
12
0
0
0
0
0
23
0
0
12
34
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
56
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _