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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLCO6A1
All Species:
20.91
Human Site:
Y489
Identified Species:
57.5
UniProt:
Q86UG4
Number Species:
8
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UG4
NP_775759.3
719
79232
Y489
F
A
G
I
N
E
D
Y
D
G
T
G
K
L
G
Chimpanzee
Pan troglodytes
XP_517854
724
78864
Y488
F
A
G
V
S
E
S
Y
N
G
T
G
E
L
G
Rhesus Macaque
Macaca mulatta
XP_001095830
723
80180
Y496
F
A
G
I
N
E
D
Y
D
G
E
G
Q
L
G
Dog
Lupus familis
XP_546002
1141
125207
Y474
L
A
G
I
N
E
D
Y
D
G
T
G
H
L
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BGD4
722
78394
Y487
F
A
G
V
S
E
S
Y
N
G
T
G
E
M
G
Rat
Rattus norvegicus
Q71MB6
724
78618
Y487
F
A
G
V
S
E
S
Y
N
G
T
G
E
M
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505407
829
89024
F607
A
K
C
G
N
E
P
F
A
G
V
S
E
A
Y
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696263
725
78339
N486
V
T
I
S
Y
Y
S
N
E
L
P
D
N
H
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001198059
772
84602
M532
V
D
Y
G
N
G
T
M
A
Y
S
G
D
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
39.5
81.8
37.5
N.A.
38.9
38.6
N.A.
36.3
N.A.
N.A.
29.6
N.A.
N.A.
N.A.
N.A.
27.5
Protein Similarity:
100
57.7
88.9
47.5
N.A.
57.2
57.3
N.A.
51.6
N.A.
N.A.
49.7
N.A.
N.A.
N.A.
N.A.
47.2
P-Site Identity:
100
66.6
86.6
86.6
N.A.
60
60
N.A.
20
N.A.
N.A.
0
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
93.3
93.3
86.6
N.A.
93.3
93.3
N.A.
33.3
N.A.
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
12
67
0
0
0
0
0
0
23
0
0
0
0
12
12
% A
% Cys:
0
0
12
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
12
0
0
0
0
34
0
34
0
0
12
12
0
0
% D
% Glu:
0
0
0
0
0
78
0
0
12
0
12
0
45
12
0
% E
% Phe:
56
0
0
0
0
0
0
12
0
0
0
0
0
0
0
% F
% Gly:
0
0
67
23
0
12
0
0
0
78
0
78
0
0
67
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
0
% H
% Ile:
0
0
12
34
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
12
0
0
0
0
0
0
0
0
0
0
12
0
0
% K
% Leu:
12
0
0
0
0
0
0
0
0
12
0
0
0
45
12
% L
% Met:
0
0
0
0
0
0
0
12
0
0
0
0
0
23
0
% M
% Asn:
0
0
0
0
56
0
0
12
34
0
0
0
12
0
0
% N
% Pro:
0
0
0
0
0
0
12
0
0
0
12
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
12
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
12
34
0
45
0
0
0
12
12
0
0
0
% S
% Thr:
0
12
0
0
0
0
12
0
0
0
56
0
0
0
0
% T
% Val:
23
0
0
34
0
0
0
0
0
0
12
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
12
0
12
12
0
67
0
12
0
0
0
0
12
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _