KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EVC2
All Species:
8.79
Human Site:
T266
Identified Species:
24.17
UniProt:
Q86UK5
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UK5
NP_667338.3
1308
147948
T266
L
K
L
P
A
Q
L
T
F
Q
S
S
S
R
N
Chimpanzee
Pan troglodytes
XP_001155684
1308
147917
T266
L
K
L
P
A
Q
L
T
F
Q
S
S
S
R
N
Rhesus Macaque
Macaca mulatta
XP_001118862
1039
119121
L151
N
L
T
S
S
G
H
L
S
P
Q
V
E
R
K
Dog
Lupus familis
XP_853893
1275
144123
L245
N
K
T
Q
L
K
A
L
F
T
I
T
A
E
E
Cat
Felis silvestris
Mouse
Mus musculus
Q8K1G2
1220
137620
R243
L
Q
G
G
M
L
S
R
C
R
I
Q
H
P
E
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001508609
724
83001
Chicken
Gallus gallus
NP_001073217
1310
150840
T260
L
T
L
P
A
Q
L
T
F
R
S
S
S
Q
N
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Q7SXE4
760
84597
Tiger Blowfish
Takifugu rubipres
NP_001027878
1344
151345
F263
D
L
P
A
F
L
T
F
S
N
A
S
Q
N
D
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.3
75.9
71.9
N.A.
67.1
N.A.
N.A.
30.2
46.4
N.A.
20.4
27.7
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99
77.3
80.2
N.A.
78.1
N.A.
N.A.
40.2
66.4
N.A.
36.8
47.7
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
6.6
13.3
N.A.
6.6
N.A.
N.A.
0
80
N.A.
0
6.6
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
13.3
33.3
N.A.
20
N.A.
N.A.
0
93.3
N.A.
0
20
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
12
34
0
12
0
0
0
12
0
12
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
12
0
0
0
0
0
0
% C
% Asp:
12
0
0
0
0
0
0
0
0
0
0
0
0
0
12
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
12
12
23
% E
% Phe:
0
0
0
0
12
0
0
12
45
0
0
0
0
0
0
% F
% Gly:
0
0
12
12
0
12
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
12
0
0
0
0
0
12
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
23
0
0
0
0
% I
% Lys:
0
34
0
0
0
12
0
0
0
0
0
0
0
0
12
% K
% Leu:
45
23
34
0
12
23
34
23
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
23
0
0
0
0
0
0
0
0
12
0
0
0
12
34
% N
% Pro:
0
0
12
34
0
0
0
0
0
12
0
0
0
12
0
% P
% Gln:
0
12
0
12
0
34
0
0
0
23
12
12
12
12
0
% Q
% Arg:
0
0
0
0
0
0
0
12
0
23
0
0
0
34
0
% R
% Ser:
0
0
0
12
12
0
12
0
23
0
34
45
34
0
0
% S
% Thr:
0
12
23
0
0
0
12
34
0
12
0
12
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
0
12
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _