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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF598
All Species:
6.97
Human Site:
S437
Identified Species:
12.78
UniProt:
Q86UK7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UK7
NP_835461.1
904
98637
S437
P
G
A
L
P
P
P
S
P
K
L
K
D
E
D
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082834
548
62617
I100
Q
H
E
K
K
Y
D
I
Y
F
A
D
G
K
V
Dog
Lupus familis
XP_547181
909
98805
S439
P
S
T
L
P
A
P
S
S
K
L
K
D
E
D
Cat
Felis silvestris
Mouse
Mus musculus
Q80YR4
908
99174
P432
L
S
N
T
L
P
P
P
S
P
E
L
K
E
E
Rat
Rattus norvegicus
NP_001099240
902
98835
P427
A
P
S
N
T
L
P
P
P
N
P
K
L
K
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233824
883
98619
A426
S
P
S
A
L
T
L
A
A
V
K
L
K
E
D
Frog
Xenopus laevis
NP_001089231
889
99603
P415
P
L
L
S
S
R
K
P
A
A
A
K
P
K
E
Zebra Danio
Brachydanio rerio
Q6PFK1
953
106893
S456
Q
S
M
I
Q
K
P
S
V
S
L
K
E
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611932
867
95920
S415
V
T
G
P
T
S
S
S
I
A
A
R
A
A
Q
Honey Bee
Apis mellifera
XP_391897
814
92277
D366
P
Q
P
L
A
V
T
D
E
N
F
P
A
L
G
Nematode Worm
Caenorhab. elegans
NP_495439
925
102667
P434
S
L
A
P
Q
A
P
P
P
N
V
R
S
S
E
Sea Urchin
Strong. purpuratus
XP_788063
833
93080
E382
K
N
K
F
K
V
E
E
D
K
E
N
E
V
L
Poplar Tree
Populus trichocarpa
XP_002302796
819
91004
S371
V
Q
P
F
E
S
L
S
A
T
D
P
E
T
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
59.4
82.7
N.A.
81.9
81.6
N.A.
N.A.
61.6
54.3
49.5
N.A.
31.4
30.7
20.4
33
Protein Similarity:
100
N.A.
59.8
87.9
N.A.
86.8
86.7
N.A.
N.A.
73.8
65.3
63.5
N.A.
46.9
45.3
36.4
49.4
P-Site Identity:
100
N.A.
0
73.3
N.A.
20
26.6
N.A.
N.A.
13.3
13.3
33.3
N.A.
6.6
13.3
20
6.6
P-Site Similarity:
100
N.A.
6.6
73.3
N.A.
26.6
40
N.A.
N.A.
26.6
26.6
53.3
N.A.
13.3
13.3
40
13.3
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
16
8
8
16
0
8
24
16
24
0
16
8
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
8
8
8
0
8
8
16
8
39
% D
% Glu:
0
0
8
0
8
0
8
8
8
0
16
0
24
31
24
% E
% Phe:
0
0
0
16
0
0
0
0
0
8
8
0
0
0
0
% F
% Gly:
0
8
8
0
0
0
0
0
0
0
0
0
8
0
8
% G
% His:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
8
0
0
0
8
8
0
0
0
0
0
0
% I
% Lys:
8
0
8
8
16
8
8
0
0
24
8
39
16
24
0
% K
% Leu:
8
16
8
24
16
8
16
0
0
0
24
16
8
8
8
% L
% Met:
0
0
8
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
8
8
0
0
0
0
0
24
0
8
0
0
0
% N
% Pro:
31
16
16
16
16
16
47
31
24
8
8
16
8
0
0
% P
% Gln:
16
16
0
0
16
0
0
0
0
0
0
0
0
0
8
% Q
% Arg:
0
0
0
0
0
8
0
0
0
0
0
16
0
0
0
% R
% Ser:
16
24
16
8
8
16
8
39
16
8
0
0
8
8
0
% S
% Thr:
0
8
8
8
16
8
8
0
0
8
0
0
0
8
8
% T
% Val:
16
0
0
0
0
16
0
0
8
8
8
0
0
8
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
8
0
0
8
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _