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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF598 All Species: 12.12
Human Site: S447 Identified Species: 22.22
UniProt: Q86UK7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UK7 NP_835461.1 904 98637 S447 L K D E D F P S L S A S T S S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082834 548 62617 L110 A D G K V Y A L Y R Q L L Q H
Dog Lupus familis XP_547181 909 98805 S449 L K D E D F P S L C A S T S S
Cat Felis silvestris
Mouse Mus musculus Q80YR4 908 99174 P442 E L K E E D F P S L C A S T S
Rat Rattus norvegicus NP_001099240 902 98835 F437 P K L K D E D F P S L C V S T
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233824 883 98619 S436 K L K E D F P S L S S S A A P
Frog Xenopus laevis NP_001089231 889 99603 F425 A K P K E E D F P S L S S V I
Zebra Danio Brachydanio rerio Q6PFK1 953 106893 S466 L K E D D F P S L S G S V V S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611932 867 95920 H425 A R A A Q S Q H P V A A V F K
Honey Bee Apis mellifera XP_391897 814 92277 A376 F P A L G P E A G S T S I S K
Nematode Worm Caenorhab. elegans NP_495439 925 102667 R444 V R S S E F P R L N K A N K P
Sea Urchin Strong. purpuratus XP_788063 833 93080 G392 E N E V L K P G G A I D P I S
Poplar Tree Populus trichocarpa XP_002302796 819 91004 Y381 D P E T T L R Y L Q A L G P S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 59.4 82.7 N.A. 81.9 81.6 N.A. N.A. 61.6 54.3 49.5 N.A. 31.4 30.7 20.4 33
Protein Similarity: 100 N.A. 59.8 87.9 N.A. 86.8 86.7 N.A. N.A. 73.8 65.3 63.5 N.A. 46.9 45.3 36.4 49.4
P-Site Identity: 100 N.A. 0 93.3 N.A. 13.3 26.6 N.A. N.A. 53.3 20 66.6 N.A. 6.6 20 20 13.3
P-Site Similarity: 100 N.A. 13.3 93.3 N.A. 40 40 N.A. N.A. 66.6 40 80 N.A. 20 26.6 53.3 26.6
Percent
Protein Identity: 20.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 35.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 20 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 26.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 0 16 8 0 0 8 8 0 8 31 24 8 8 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 8 8 8 0 0 0 % C
% Asp: 8 8 16 8 39 8 16 0 0 0 0 8 0 0 0 % D
% Glu: 16 0 24 31 24 16 8 0 0 0 0 0 0 0 0 % E
% Phe: 8 0 0 0 0 39 8 16 0 0 0 0 0 8 0 % F
% Gly: 0 0 8 0 8 0 0 8 16 0 8 0 8 0 0 % G
% His: 0 0 0 0 0 0 0 8 0 0 0 0 0 0 8 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 8 0 8 8 8 % I
% Lys: 8 39 16 24 0 8 0 0 0 0 8 0 0 8 16 % K
% Leu: 24 16 8 8 8 8 0 8 47 8 16 16 8 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 0 0 0 0 0 0 0 8 0 0 8 0 0 % N
% Pro: 8 16 8 0 0 8 47 8 24 0 0 0 8 8 16 % P
% Gln: 0 0 0 0 8 0 8 0 0 8 8 0 0 8 0 % Q
% Arg: 0 16 0 0 0 0 8 8 0 8 0 0 0 0 0 % R
% Ser: 0 0 8 8 0 8 0 31 8 47 8 47 16 31 47 % S
% Thr: 0 0 0 8 8 0 0 0 0 0 8 0 16 8 8 % T
% Val: 8 0 0 8 8 0 0 0 0 8 0 0 24 16 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 8 0 8 8 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _