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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF598
All Species:
12.12
Human Site:
S449
Identified Species:
22.22
UniProt:
Q86UK7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UK7
NP_835461.1
904
98637
S449
D
E
D
F
P
S
L
S
A
S
T
S
S
S
C
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082834
548
62617
R112
G
K
V
Y
A
L
Y
R
Q
L
L
Q
H
E
C
Dog
Lupus familis
XP_547181
909
98805
C451
D
E
D
F
P
S
L
C
A
S
T
S
S
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q80YR4
908
99174
L444
K
E
E
D
F
P
S
L
C
A
S
T
S
S
C
Rat
Rattus norvegicus
NP_001099240
902
98835
S439
L
K
D
E
D
F
P
S
L
C
V
S
T
S
C
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233824
883
98619
S438
K
E
D
F
P
S
L
S
S
S
A
A
P
A
I
Frog
Xenopus laevis
NP_001089231
889
99603
S427
P
K
E
E
D
F
P
S
L
S
S
V
I
S
S
Zebra Danio
Brachydanio rerio
Q6PFK1
953
106893
S468
E
D
D
F
P
S
L
S
G
S
V
V
S
S
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611932
867
95920
V427
A
A
Q
S
Q
H
P
V
A
A
V
F
K
K
P
Honey Bee
Apis mellifera
XP_391897
814
92277
S378
A
L
G
P
E
A
G
S
T
S
I
S
K
T
V
Nematode Worm
Caenorhab. elegans
NP_495439
925
102667
N446
S
S
E
F
P
R
L
N
K
A
N
K
P
A
A
Sea Urchin
Strong. purpuratus
XP_788063
833
93080
A394
E
V
L
K
P
G
G
A
I
D
P
I
S
N
R
Poplar Tree
Populus trichocarpa
XP_002302796
819
91004
Q383
E
T
T
L
R
Y
L
Q
A
L
G
P
S
S
R
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
59.4
82.7
N.A.
81.9
81.6
N.A.
N.A.
61.6
54.3
49.5
N.A.
31.4
30.7
20.4
33
Protein Similarity:
100
N.A.
59.8
87.9
N.A.
86.8
86.7
N.A.
N.A.
73.8
65.3
63.5
N.A.
46.9
45.3
36.4
49.4
P-Site Identity:
100
N.A.
6.6
86.6
N.A.
26.6
33.3
N.A.
N.A.
53.3
20
60
N.A.
6.6
20
20
13.3
P-Site Similarity:
100
N.A.
20
86.6
N.A.
53.3
46.6
N.A.
N.A.
73.3
40
73.3
N.A.
13.3
33.3
46.6
33.3
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
16
8
0
0
8
8
0
8
31
24
8
8
0
16
8
% A
% Cys:
0
0
0
0
0
0
0
8
8
8
0
0
0
0
31
% C
% Asp:
16
8
39
8
16
0
0
0
0
8
0
0
0
0
0
% D
% Glu:
24
31
24
16
8
0
0
0
0
0
0
0
0
8
0
% E
% Phe:
0
0
0
39
8
16
0
0
0
0
0
8
0
0
0
% F
% Gly:
8
0
8
0
0
8
16
0
8
0
8
0
0
0
0
% G
% His:
0
0
0
0
0
8
0
0
0
0
0
0
8
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
8
0
8
8
8
0
8
% I
% Lys:
16
24
0
8
0
0
0
0
8
0
0
8
16
8
0
% K
% Leu:
8
8
8
8
0
8
47
8
16
16
8
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
8
0
0
8
0
0
8
0
% N
% Pro:
8
0
0
8
47
8
24
0
0
0
8
8
16
0
16
% P
% Gln:
0
0
8
0
8
0
0
8
8
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
8
0
8
0
0
0
0
0
0
16
% R
% Ser:
8
8
0
8
0
31
8
47
8
47
16
31
47
54
16
% S
% Thr:
0
8
8
0
0
0
0
0
8
0
16
8
8
8
0
% T
% Val:
0
8
8
0
0
0
0
8
0
0
24
16
0
0
8
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
8
8
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _