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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF598
All Species:
5.15
Human Site:
S574
Identified Species:
9.44
UniProt:
Q86UK7
Number Species:
12
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UK7
NP_835461.1
904
98637
S574
T
R
P
T
G
S
V
S
S
T
L
G
L
A
S
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082834
548
62617
R236
A
Y
L
R
E
H
F
R
E
K
H
F
L
C
E
Dog
Lupus familis
XP_547181
909
98805
L581
T
V
A
V
S
S
L
L
A
L
A
S
T
Q
T
Cat
Felis silvestris
Mouse
Mus musculus
Q80YR4
908
99174
A572
V
A
V
S
S
L
L
A
P
A
T
N
Q
S
S
Rat
Rattus norvegicus
NP_001099240
902
98835
A566
V
A
V
S
S
L
L
A
P
V
A
N
Q
N
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233824
883
98619
T564
L
A
A
S
T
S
Q
T
F
T
K
V
S
K
K
Frog
Xenopus laevis
NP_001089231
889
99603
K555
P
T
M
F
D
I
S
K
L
L
S
S
P
T
A
Zebra Danio
Brachydanio rerio
Q6PFK1
953
106893
S613
V
P
T
M
L
D
I
S
T
L
L
T
V
K
G
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611932
867
95920
L551
L
K
K
S
A
P
K
L
T
A
A
E
F
P
S
Honey Bee
Apis mellifera
XP_391897
814
92277
L502
S
G
E
D
F
P
T
L
S
K
S
S
R
S
K
Nematode Worm
Caenorhab. elegans
NP_495439
925
102667
S574
E
S
S
S
S
A
P
S
S
G
R
L
D
F
P
Sea Urchin
Strong. purpuratus
XP_788063
833
93080
L519
L
S
S
I
A
S
L
L
G
G
N
Q
K
K
N
Poplar Tree
Populus trichocarpa
XP_002302796
819
91004
S507
R
G
H
P
S
A
G
S
V
G
I
S
G
T
T
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
59.4
82.7
N.A.
81.9
81.6
N.A.
N.A.
61.6
54.3
49.5
N.A.
31.4
30.7
20.4
33
Protein Similarity:
100
N.A.
59.8
87.9
N.A.
86.8
86.7
N.A.
N.A.
73.8
65.3
63.5
N.A.
46.9
45.3
36.4
49.4
P-Site Identity:
100
N.A.
6.6
13.3
N.A.
6.6
6.6
N.A.
N.A.
13.3
0
13.3
N.A.
6.6
6.6
13.3
6.6
P-Site Similarity:
100
N.A.
6.6
33.3
N.A.
33.3
26.6
N.A.
N.A.
26.6
6.6
33.3
N.A.
26.6
20
26.6
20
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
24
16
0
16
16
0
16
8
16
24
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
8
0
% C
% Asp:
0
0
0
8
8
8
0
0
0
0
0
0
8
0
0
% D
% Glu:
8
0
8
0
8
0
0
0
8
0
0
8
0
0
8
% E
% Phe:
0
0
0
8
8
0
8
0
8
0
0
8
8
8
0
% F
% Gly:
0
16
0
0
8
0
8
0
8
24
0
8
8
0
8
% G
% His:
0
0
8
0
0
8
0
0
0
0
8
0
0
0
0
% H
% Ile:
0
0
0
8
0
8
8
0
0
0
8
0
0
0
0
% I
% Lys:
0
8
8
0
0
0
8
8
0
16
8
0
8
24
16
% K
% Leu:
24
0
8
0
8
16
31
31
8
24
16
8
16
0
0
% L
% Met:
0
0
8
8
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
8
16
0
8
8
% N
% Pro:
8
8
8
8
0
16
8
0
16
0
0
0
8
8
8
% P
% Gln:
0
0
0
0
0
0
8
0
0
0
0
8
16
8
0
% Q
% Arg:
8
8
0
8
0
0
0
8
0
0
8
0
8
0
0
% R
% Ser:
8
16
16
39
39
31
8
31
24
0
16
31
8
16
31
% S
% Thr:
16
8
8
8
8
0
8
8
16
16
8
8
8
16
16
% T
% Val:
24
8
16
8
0
0
8
0
8
8
0
8
8
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
8
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _