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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF598 All Species: 7.27
Human Site: T395 Identified Species: 13.33
UniProt: Q86UK7 Number Species: 12
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UK7 NP_835461.1 904 98637 T395 G P R R S P R T Q G E G P G P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082834 548 62617 E61 T K M R V L C E Q R Y C A V C
Dog Lupus familis XP_547181 909 98805 T399 G P R R P A R T Q G E G P G L
Cat Felis silvestris
Mouse Mus musculus Q80YR4 908 99174 A393 G H R R L P R A Q G E G S G S
Rat Rattus norvegicus NP_001099240 902 98835 R384 P E E S R G H R R L P R A Q G
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233824 883 98619 S385 S S K R V P K S S S E A T G P
Frog Xenopus laevis NP_001089231 889 99603 P364 K G K A S S K P T T D L V G A
Zebra Danio Brachydanio rerio Q6PFK1 953 106893 R415 R N N R S T A R P T N D T Q A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611932 867 95920 P376 P S V S L V R P P P P S M R N
Honey Bee Apis mellifera XP_391897 814 92277 E327 S V D V Q S T E E F P T L G N
Nematode Worm Caenorhab. elegans NP_495439 925 102667 T390 V V Q R Q V E T N P Q S D P S
Sea Urchin Strong. purpuratus XP_788063 833 93080 V343 D E R K K K M V V Q P Q K E E
Poplar Tree Populus trichocarpa XP_002302796 819 91004 L332 S I A I Q A S L E A A Y S E S
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 59.4 82.7 N.A. 81.9 81.6 N.A. N.A. 61.6 54.3 49.5 N.A. 31.4 30.7 20.4 33
Protein Similarity: 100 N.A. 59.8 87.9 N.A. 86.8 86.7 N.A. N.A. 73.8 65.3 63.5 N.A. 46.9 45.3 36.4 49.4
P-Site Identity: 100 N.A. 13.3 80 N.A. 66.6 0 N.A. N.A. 33.3 13.3 13.3 N.A. 6.6 6.6 13.3 6.6
P-Site Similarity: 100 N.A. 13.3 80 N.A. 66.6 6.6 N.A. N.A. 53.3 33.3 13.3 N.A. 6.6 13.3 26.6 13.3
Percent
Protein Identity: 20.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 35.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 6.6 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 8 8 0 16 8 8 0 8 8 8 16 0 16 % A
% Cys: 0 0 0 0 0 0 8 0 0 0 0 8 0 0 8 % C
% Asp: 8 0 8 0 0 0 0 0 0 0 8 8 8 0 0 % D
% Glu: 0 16 8 0 0 0 8 16 16 0 31 0 0 16 8 % E
% Phe: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % F
% Gly: 24 8 0 0 0 8 0 0 0 24 0 24 0 47 8 % G
% His: 0 8 0 0 0 0 8 0 0 0 0 0 0 0 0 % H
% Ile: 0 8 0 8 0 0 0 0 0 0 0 0 0 0 0 % I
% Lys: 8 8 16 8 8 8 16 0 0 0 0 0 8 0 0 % K
% Leu: 0 0 0 0 16 8 0 8 0 8 0 8 8 0 8 % L
% Met: 0 0 8 0 0 0 8 0 0 0 0 0 8 0 0 % M
% Asn: 0 8 8 0 0 0 0 0 8 0 8 0 0 0 16 % N
% Pro: 16 16 0 0 8 24 0 16 16 16 31 0 16 8 16 % P
% Gln: 0 0 8 0 24 0 0 0 31 8 8 8 0 16 0 % Q
% Arg: 8 0 31 54 8 0 31 16 8 8 0 8 0 8 0 % R
% Ser: 24 16 0 16 24 16 8 8 8 8 0 16 16 0 24 % S
% Thr: 8 0 0 0 0 8 8 24 8 16 0 8 16 0 0 % T
% Val: 8 16 8 8 16 16 0 8 8 0 0 0 8 8 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 8 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _