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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZNF598 All Species: 17.27
Human Site: T637 Identified Species: 31.67
UniProt: Q86UK7 Number Species: 12
    Phosphosite Substitution
    Charge Score: -0.08
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UK7 NP_835461.1 904 98637 T637 A V V V N G H T E G P A P A R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001082834 548 62617 G299 R H S R R N E G V V G G E D Y
Dog Lupus familis XP_547181 909 98805 T644 A L I V N G H T E G P A P A R
Cat Felis silvestris
Mouse Mus musculus Q80YR4 908 99174 S635 T I V V N G H S E G S A L V R
Rat Rattus norvegicus NP_001099240 902 98835 S629 T I V V N G H S E G S A L A W
Wallaby Macropus eugenll
Platypus Ornith. anatinus
Chicken Gallus gallus XP_001233824 883 98619 S627 A A V V N G H S E K S L A I C
Frog Xenopus laevis NP_001089231 889 99603 L618 T P P A N S I L S D K S N T V
Zebra Danio Brachydanio rerio Q6PFK1 953 106893 A676 G L N K A P T A P K T N S I V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611932 867 95920 S614 P V L P S P T S K P A P K A S
Honey Bee Apis mellifera XP_391897 814 92277 T565 T D N I N N E T V V N T N I G
Nematode Worm Caenorhab. elegans NP_495439 925 102667 K637 K N K I S V P K T E V W S S L
Sea Urchin Strong. purpuratus XP_788063 833 93080 S582 T V Q K P A M S V P S Q P T T
Poplar Tree Populus trichocarpa XP_002302796 819 91004 L570 F Q T A N K S L V E K I R A A
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 59.4 82.7 N.A. 81.9 81.6 N.A. N.A. 61.6 54.3 49.5 N.A. 31.4 30.7 20.4 33
Protein Similarity: 100 N.A. 59.8 87.9 N.A. 86.8 86.7 N.A. N.A. 73.8 65.3 63.5 N.A. 46.9 45.3 36.4 49.4
P-Site Identity: 100 N.A. 0 86.6 N.A. 60 60 N.A. N.A. 46.6 6.6 0 N.A. 13.3 13.3 0 13.3
P-Site Similarity: 100 N.A. 0 100 N.A. 73.3 73.3 N.A. N.A. 53.3 13.3 6.6 N.A. 40 20 20 20
Percent
Protein Identity: 20.3 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 35.7 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 13.3 N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 24 8 0 16 8 8 0 8 0 0 8 31 8 39 8 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % C
% Asp: 0 8 0 0 0 0 0 0 0 8 0 0 0 8 0 % D
% Glu: 0 0 0 0 0 0 16 0 39 16 0 0 8 0 0 % E
% Phe: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 8 0 0 0 0 39 0 8 0 31 8 8 0 0 8 % G
% His: 0 8 0 0 0 0 39 0 0 0 0 0 0 0 0 % H
% Ile: 0 16 8 16 0 0 8 0 0 0 0 8 0 24 0 % I
% Lys: 8 0 8 16 0 8 0 8 8 16 16 0 8 0 0 % K
% Leu: 0 16 8 0 0 0 0 16 0 0 0 8 16 0 8 % L
% Met: 0 0 0 0 0 0 8 0 0 0 0 0 0 0 0 % M
% Asn: 0 8 16 0 62 16 0 0 0 0 8 8 16 0 0 % N
% Pro: 8 8 8 8 8 16 8 0 8 16 16 8 24 0 0 % P
% Gln: 0 8 8 0 0 0 0 0 0 0 0 8 0 0 0 % Q
% Arg: 8 0 0 8 8 0 0 0 0 0 0 0 8 0 24 % R
% Ser: 0 0 8 0 16 8 8 39 8 0 31 8 16 8 8 % S
% Thr: 39 0 8 0 0 0 16 24 8 0 8 8 0 16 8 % T
% Val: 0 24 31 39 0 8 0 0 31 16 8 0 0 8 16 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 8 0 0 8 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 8 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _