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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ZNF598
All Species:
27.27
Human Site:
Y224
Identified Species:
50
UniProt:
Q86UK7
Number Species:
12
Phosphosite Substitution
Charge Score:
0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UK7
NP_835461.1
904
98637
Y224
D
S
D
G
A
Q
D
Y
Y
S
D
Y
A
Y
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001082834
548
62617
Dog
Lupus familis
XP_547181
909
98805
Y224
D
S
D
G
A
Q
D
Y
Y
S
D
Y
A
Y
L
Cat
Felis silvestris
Mouse
Mus musculus
Q80YR4
908
99174
Y222
D
S
D
G
A
Q
D
Y
Y
S
D
Y
A
Y
L
Rat
Rattus norvegicus
NP_001099240
902
98835
Y221
D
A
D
G
A
Q
D
Y
Y
S
D
Y
A
Y
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233824
883
98619
Y216
D
S
D
G
A
Q
E
Y
Y
S
D
Y
E
Y
L
Frog
Xenopus laevis
NP_001089231
889
99603
Y189
D
S
E
G
A
Q
E
Y
Y
S
D
Y
T
F
L
Zebra Danio
Brachydanio rerio
Q6PFK1
953
106893
Y252
D
A
D
G
A
Q
E
Y
Y
S
D
Y
Q
Y
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_611932
867
95920
D220
N
K
R
Y
V
D
R
D
E
L
F
R
H
L
R
Honey Bee
Apis mellifera
XP_391897
814
92277
M173
E
F
C
D
Q
R
Y
M
D
N
D
E
L
F
R
Nematode Worm
Caenorhab. elegans
NP_495439
925
102667
C215
S
R
H
E
Q
S
Y
C
H
I
C
T
D
N
L
Sea Urchin
Strong. purpuratus
XP_788063
833
93080
H189
D
N
D
E
L
H
R
H
L
R
K
D
H
Y
F
Poplar Tree
Populus trichocarpa
XP_002302796
819
91004
S178
Q
H
I
S
T
G
D
S
D
V
D
G
S
E
S
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
59.4
82.7
N.A.
81.9
81.6
N.A.
N.A.
61.6
54.3
49.5
N.A.
31.4
30.7
20.4
33
Protein Similarity:
100
N.A.
59.8
87.9
N.A.
86.8
86.7
N.A.
N.A.
73.8
65.3
63.5
N.A.
46.9
45.3
36.4
49.4
P-Site Identity:
100
N.A.
0
100
N.A.
100
93.3
N.A.
N.A.
86.6
73.3
80
N.A.
0
6.6
6.6
20
P-Site Similarity:
100
N.A.
0
100
N.A.
100
100
N.A.
N.A.
93.3
93.3
93.3
N.A.
6.6
33.3
13.3
33.3
Percent
Protein Identity:
20.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
16
0
0
54
0
0
0
0
0
0
0
31
0
0
% A
% Cys:
0
0
8
0
0
0
0
8
0
0
8
0
0
0
0
% C
% Asp:
62
0
54
8
0
8
39
8
16
0
70
8
8
0
0
% D
% Glu:
8
0
8
16
0
0
24
0
8
0
0
8
8
8
0
% E
% Phe:
0
8
0
0
0
0
0
0
0
0
8
0
0
16
8
% F
% Gly:
0
0
0
54
0
8
0
0
0
0
0
8
0
0
0
% G
% His:
0
8
8
0
0
8
0
8
8
0
0
0
16
0
0
% H
% Ile:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% I
% Lys:
0
8
0
0
0
0
0
0
0
0
8
0
0
0
0
% K
% Leu:
0
0
0
0
8
0
0
0
8
8
0
0
8
8
62
% L
% Met:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% M
% Asn:
8
8
0
0
0
0
0
0
0
8
0
0
0
8
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
8
0
0
0
16
54
0
0
0
0
0
0
8
0
0
% Q
% Arg:
0
8
8
0
0
8
16
0
0
8
0
8
0
0
16
% R
% Ser:
8
39
0
8
0
8
0
8
0
54
0
0
8
0
8
% S
% Thr:
0
0
0
0
8
0
0
0
0
0
0
8
8
0
0
% T
% Val:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
8
0
0
16
54
54
0
0
54
0
54
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _