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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ZFHX4 All Species: 7.88
Human Site: S1845 Identified Species: 19.26
UniProt: Q86UP3 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UP3 NP_078997.3 3567 393730 S1845 K D T K K Q K S L E P S I P P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001089817 3156 348587 Q1544 H P P Q S P A Q I Q M Q L Q H
Dog Lupus familis XP_853266 3452 379865 P1773 A Q Q Y Q P P P Q P A A S K L
Cat Felis silvestris
Mouse Mus musculus Q9JJN2 3550 392304 K1857 K D S K D I K K Q K S L E P C
Rat Rattus norvegicus XP_226964 3593 395739 S1870 K D V K K Q K S L E P C I P P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509863 3710 407348 S1933 K E F A P G A S S E P S M L P
Chicken Gallus gallus O73590 3573 394529 S1831 D M K K P K S S E P A I P P P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_684360 2686 299027 F1074 E H I H G Q F F P Y V E L E K
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393785 2962 326678 A1350 L I S V V P P A S P T E S P D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798150 3296 366823 A1684 S T D P N V A A L L S Q D A L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 87.1 90.4 N.A. 90.8 91.8 N.A. 55.3 90.2 N.A. 52.6 N.A. N.A. 21.1 N.A. 26
Protein Similarity: 100 N.A. 87.6 92.4 N.A. 94.1 94.9 N.A. 68.1 94 N.A. 61.7 N.A. N.A. 36.2 N.A. 41.1
P-Site Identity: 100 N.A. 0 0 N.A. 33.3 86.6 N.A. 40 26.6 N.A. 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 N.A. 26.6 13.3 N.A. 46.6 86.6 N.A. 53.3 33.3 N.A. 20 N.A. N.A. 20 N.A. 13.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 10 0 0 30 20 0 0 20 10 0 10 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 10 0 0 10 % C
% Asp: 10 30 10 0 10 0 0 0 0 0 0 0 10 0 10 % D
% Glu: 10 10 0 0 0 0 0 0 10 30 0 20 10 10 0 % E
% Phe: 0 0 10 0 0 0 10 10 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 10 10 0 0 0 0 0 0 0 0 0 % G
% His: 10 10 0 10 0 0 0 0 0 0 0 0 0 0 10 % H
% Ile: 0 10 10 0 0 10 0 0 10 0 0 10 20 0 0 % I
% Lys: 40 0 10 40 20 10 30 10 0 10 0 0 0 10 10 % K
% Leu: 10 0 0 0 0 0 0 0 30 10 0 10 20 10 20 % L
% Met: 0 10 0 0 0 0 0 0 0 0 10 0 10 0 0 % M
% Asn: 0 0 0 0 10 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 10 10 10 20 30 20 10 10 30 30 0 10 50 40 % P
% Gln: 0 10 10 10 10 30 0 10 20 10 0 20 0 10 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % R
% Ser: 10 0 20 0 10 0 10 40 20 0 20 20 20 0 0 % S
% Thr: 0 10 10 0 0 0 0 0 0 0 10 0 0 0 0 % T
% Val: 0 0 10 10 10 10 0 0 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 10 0 0 0 0 0 10 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _