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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
GTF2IRD2
All Species:
13.64
Human Site:
S726
Identified Species:
50
UniProt:
Q86UP8
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UP8
NP_775808.2
949
107231
S726
V
L
K
R
F
F
E
S
L
E
E
I
D
S
F
Chimpanzee
Pan troglodytes
XP_001153190
949
107163
S726
V
L
K
R
F
F
E
S
L
E
E
I
D
S
F
Rhesus Macaque
Macaca mulatta
XP_001084899
950
107471
S727
V
L
K
R
F
F
E
S
L
E
E
I
D
S
F
Dog
Lupus familis
XP_849558
948
107092
S725
V
L
K
R
F
F
E
S
L
E
E
I
D
S
F
Cat
Felis silvestris
Mouse
Mus musculus
Q99NI3
936
104559
L714
W
L
G
R
G
L
V
L
R
R
F
F
E
S
L
Rat
Rattus norvegicus
Q5U2Y1
979
110196
F746
P
F
A
L
F
E
S
F
P
E
D
F
Y
V
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510406
994
111440
E747
F
P
E
D
F
Y
V
E
G
L
P
E
G
V
P
Chicken
Gallus gallus
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99
92.4
88.3
N.A.
78.9
34
N.A.
32.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.3
94.9
92.9
N.A.
87.7
50.9
N.A.
48.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
100
N.A.
20
13.3
N.A.
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
100
N.A.
26.6
20
N.A.
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
15
0
0
0
0
0
0
15
0
58
0
0
% D
% Glu:
0
0
15
0
0
15
58
15
0
72
58
15
15
0
15
% E
% Phe:
15
15
0
0
86
58
0
15
0
0
15
29
0
0
58
% F
% Gly:
0
0
15
0
15
0
0
0
15
0
0
0
15
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
58
0
0
0
% I
% Lys:
0
0
58
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
72
0
15
0
15
0
15
58
15
0
0
0
0
15
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
15
15
0
0
0
0
0
0
15
0
15
0
0
0
15
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
72
0
0
0
0
15
15
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
15
58
0
0
0
0
0
72
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
58
0
0
0
0
0
29
0
0
0
0
0
0
29
0
% V
% Trp:
15
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
15
0
0
0
0
0
0
15
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _