KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LHFPL3
All Species:
4.55
Human Site:
S220
Identified Species:
11.11
UniProt:
Q86UP9
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UP9
NP_945351.1
222
24702
S220
K
V
L
L
S
Q
Y
S
L
E
_
_
_
_
_
Chimpanzee
Pan troglodytes
XP_527854
230
25034
K221
S
L
M
A
E
E
L
K
A
E
N
K
D
D
G
Rhesus Macaque
Macaca mulatta
XP_001096555
247
26972
V221
K
D
F
V
G
S
T
V
S
S
V
L
R
P
G
Dog
Lupus familis
XP_541784
307
32950
V281
K
D
F
V
G
S
T
V
S
S
V
L
R
P
G
Cat
Felis silvestris
Mouse
Mus musculus
Q9CTN8
222
24668
S220
K
V
L
L
S
Q
Y
S
L
E
_
_
_
_
_
Rat
Rattus norvegicus
Q7TSY2
247
27031
V221
K
D
F
V
G
T
T
V
S
S
V
L
R
P
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001516205
258
28431
C223
K
G
N
P
D
L
P
C
H
D
I
S
L
K
G
Chicken
Gallus gallus
Q7ZZL8
221
24401
G219
K
V
E
S
K
E
E
G
N
E
_
_
_
_
_
Frog
Xenopus laevis
Q66IV3
218
23764
Zebra Danio
Brachydanio rerio
Q6DHB5
216
23481
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
92.1
69.2
56.3
N.A.
97.7
69.2
N.A.
58.1
71.1
84.2
78.3
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92.6
79.3
64.1
N.A.
98.6
79.3
N.A.
72.4
84.2
90.5
88.7
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
6.6
6.6
6.6
N.A.
100
6.6
N.A.
6.6
30
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
33.3
20
20
N.A.
100
20
N.A.
26.6
40
0
0
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
30
0
0
10
0
0
0
0
10
0
0
10
10
0
% D
% Glu:
0
0
10
0
10
20
10
0
0
40
0
0
0
0
0
% E
% Phe:
0
0
30
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
10
0
0
30
0
0
10
0
0
0
0
0
0
50
% G
% His:
0
0
0
0
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% I
% Lys:
70
0
0
0
10
0
0
10
0
0
0
10
0
10
0
% K
% Leu:
0
10
20
20
0
10
10
0
20
0
0
30
10
0
0
% L
% Met:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
0
10
0
10
0
0
0
0
% N
% Pro:
0
0
0
10
0
0
10
0
0
0
0
0
0
30
0
% P
% Gln:
0
0
0
0
0
20
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
30
0
0
% R
% Ser:
10
0
0
10
20
20
0
20
30
30
0
10
0
0
0
% S
% Thr:
0
0
0
0
0
10
30
0
0
0
0
0
0
0
0
% T
% Val:
0
30
0
30
0
0
0
30
0
0
30
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
20
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
30
30
30
30
30
% _