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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: RIMS1 All Species: 9.7
Human Site: S1222 Identified Species: 23.7
UniProt: Q86UR5 Number Species: 9
    Phosphosite Substitution
    Charge Score: 0.11
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UR5 NP_055804.2 1692 189073 S1222 S R S S E H S S I R T L C S M
Chimpanzee Pan troglodytes XP_001157433 1557 176218 T1107 P R T G S V Q T S P S S T P V
Rhesus Macaque Macaca mulatta NP_001032357 1028 115316 P578 S H P V T W Q P S K E G D R L
Dog Lupus familis XP_538998 1691 188872 S1221 S R S S E H S S V R A L C S T
Cat Felis silvestris
Mouse Mus musculus Q99NE5 1463 163143 P1013 G G S A P P S P L L T R T H R
Rat Rattus norvegicus Q9JIR4 1615 179636 P1156 C S M H H L A P G G S A P P S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509917 1381 156408 D931 L E T A L L D D E A H W Y K L
Chicken Gallus gallus XP_419884 1695 190353 S1225 S R S S E H S S V R A L C S V
Frog Xenopus laevis
Zebra Danio Brachydanio rerio XP_001920695 1451 162180 N1001 L N L R L T P N G Q G A T T L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q22366 1563 175460 N1113 N M I G R A Y N R R Q Q R R P
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 58.2 60.2 94 N.A. 81.5 87.8 N.A. 47.4 87.6 N.A. 55.7 N.A. N.A. N.A. 21.1 N.A.
Protein Similarity: 100 70.5 60.3 96.3 N.A. 82.8 90 N.A. 58.4 92.4 N.A. 64.8 N.A. N.A. N.A. 37.2 N.A.
P-Site Identity: 100 6.6 6.6 80 N.A. 20 0 N.A. 0 80 N.A. 0 N.A. N.A. N.A. 6.6 N.A.
P-Site Similarity: 100 33.3 20 86.6 N.A. 33.3 13.3 N.A. 20 93.3 N.A. 26.6 N.A. N.A. N.A. 20 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 20 0 10 10 0 0 10 20 20 0 0 0 % A
% Cys: 10 0 0 0 0 0 0 0 0 0 0 0 30 0 0 % C
% Asp: 0 0 0 0 0 0 10 10 0 0 0 0 10 0 0 % D
% Glu: 0 10 0 0 30 0 0 0 10 0 10 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 10 0 20 0 0 0 0 20 10 10 10 0 0 0 % G
% His: 0 10 0 10 10 30 0 0 0 0 10 0 0 10 0 % H
% Ile: 0 0 10 0 0 0 0 0 10 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 0 0 10 0 % K
% Leu: 20 0 10 0 20 20 0 0 10 10 0 30 0 0 30 % L
% Met: 0 10 10 0 0 0 0 0 0 0 0 0 0 0 10 % M
% Asn: 10 10 0 0 0 0 0 20 0 0 0 0 0 0 0 % N
% Pro: 10 0 10 0 10 10 10 30 0 10 0 0 10 20 10 % P
% Gln: 0 0 0 0 0 0 20 0 0 10 10 10 0 0 0 % Q
% Arg: 0 40 0 10 10 0 0 0 10 40 0 10 10 20 10 % R
% Ser: 40 10 40 30 10 0 40 30 20 0 20 10 0 30 10 % S
% Thr: 0 0 20 0 10 10 0 10 0 0 20 0 30 10 10 % T
% Val: 0 0 0 10 0 10 0 0 20 0 0 0 0 0 20 % V
% Trp: 0 0 0 0 0 10 0 0 0 0 0 10 0 0 0 % W
% Tyr: 0 0 0 0 0 0 10 0 0 0 0 0 10 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _