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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RIMS1
All Species:
4.55
Human Site:
S474
Identified Species:
11.11
UniProt:
Q86UR5
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UR5
NP_055804.2
1692
189073
S474
Q
E
P
L
R
K
Q
S
R
L
D
P
S
S
A
Chimpanzee
Pan troglodytes
XP_001157433
1557
176218
S372
E
R
R
H
S
D
V
S
L
A
N
A
D
L
E
Rhesus Macaque
Macaca mulatta
NP_001032357
1028
115316
Dog
Lupus familis
XP_538998
1691
188872
Q473
A
Q
E
P
L
R
K
Q
S
R
L
D
P
S
S
Cat
Felis silvestris
Mouse
Mus musculus
Q99NE5
1463
163143
E278
S
Q
Q
A
L
G
P
E
Q
K
Q
A
S
R
S
Rat
Rattus norvegicus
Q9JIR4
1615
179636
P418
R
H
S
D
V
A
L
P
H
T
E
A
A
A
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509917
1381
156408
P196
G
S
N
R
V
Y
E
P
P
Q
V
V
P
R
G
Chicken
Gallus gallus
XP_419884
1695
190353
S476
H
D
T
F
K
K
Q
S
R
L
D
P
S
S
A
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001920695
1451
162180
D266
K
K
P
P
A
A
S
D
Q
N
G
K
P
G
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q22366
1563
175460
N378
H
V
E
D
D
G
M
N
Q
R
P
T
F
Y
T
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
58.2
60.2
94
N.A.
81.5
87.8
N.A.
47.4
87.6
N.A.
55.7
N.A.
N.A.
N.A.
21.1
N.A.
Protein Similarity:
100
70.5
60.3
96.3
N.A.
82.8
90
N.A.
58.4
92.4
N.A.
64.8
N.A.
N.A.
N.A.
37.2
N.A.
P-Site Identity:
100
6.6
0
6.6
N.A.
6.6
6.6
N.A.
0
66.6
N.A.
6.6
N.A.
N.A.
N.A.
0
N.A.
P-Site Similarity:
100
20
0
33.3
N.A.
26.6
33.3
N.A.
6.6
80
N.A.
26.6
N.A.
N.A.
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
10
10
20
0
0
0
10
0
30
10
10
30
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
10
0
20
10
10
0
10
0
0
20
10
10
0
0
% D
% Glu:
10
10
20
0
0
0
10
10
0
0
10
0
0
0
10
% E
% Phe:
0
0
0
10
0
0
0
0
0
0
0
0
10
0
0
% F
% Gly:
10
0
0
0
0
20
0
0
0
0
10
0
0
10
10
% G
% His:
20
10
0
10
0
0
0
0
10
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
10
10
0
0
10
20
10
0
0
10
0
10
0
0
0
% K
% Leu:
0
0
0
10
20
0
10
0
10
20
10
0
0
10
0
% L
% Met:
0
0
0
0
0
0
10
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
10
0
0
0
0
10
0
10
10
0
0
0
0
% N
% Pro:
0
0
20
20
0
0
10
20
10
0
10
20
30
0
10
% P
% Gln:
10
20
10
0
0
0
20
10
30
10
10
0
0
0
0
% Q
% Arg:
10
10
10
10
10
10
0
0
20
20
0
0
0
20
0
% R
% Ser:
10
10
10
0
10
0
10
30
10
0
0
0
30
30
20
% S
% Thr:
0
0
10
0
0
0
0
0
0
10
0
10
0
0
10
% T
% Val:
0
10
0
0
20
0
10
0
0
0
10
10
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
10
0
0
0
0
0
0
0
10
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _