KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SMG6
All Species:
2.73
Human Site:
S342
Identified Species:
6.67
UniProt:
Q86US8
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86US8
NP_060045.4
1419
160462
S342
G
E
G
E
Q
K
N
S
A
K
E
Y
R
G
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_548319
1527
171816
N451
G
E
G
E
Q
K
S
N
G
K
E
N
R
G
T
Cat
Felis silvestris
Mouse
Mus musculus
P61406
1418
160477
N341
G
E
G
E
Q
K
S
N
G
K
E
N
R
S
A
Rat
Rattus norvegicus
NP_001099278
1472
165733
N395
G
E
G
E
Q
K
S
N
G
K
E
N
R
G
A
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509588
959
106964
Chicken
Gallus gallus
XP_001234885
1419
159567
N381
S
E
S
E
W
S
S
N
G
R
E
V
K
G
H
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_696418
1546
172554
R442
G
Q
T
R
S
R
R
R
T
A
R
T
L
S
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_651321
948
108473
Honey Bee
Apis mellifera
XP_393289
1688
192186
E553
V
E
L
S
E
K
L
E
A
E
R
A
S
R
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_794411
1745
199805
S474
E
E
F
D
T
V
S
S
S
K
D
L
R
I
T
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
85.5
N.A.
90.8
88
N.A.
40.7
69.6
N.A.
49.3
N.A.
21.7
29.7
N.A.
24.4
Protein Similarity:
100
N.A.
N.A.
88.7
N.A.
95.1
91.9
N.A.
49.8
80.3
N.A.
64.4
N.A.
36.2
45.5
N.A.
41.7
P-Site Identity:
100
N.A.
N.A.
73.3
N.A.
60
66.6
N.A.
0
26.6
N.A.
6.6
N.A.
0
20
N.A.
33.3
P-Site Similarity:
100
N.A.
N.A.
86.6
N.A.
73.3
80
N.A.
0
53.3
N.A.
26.6
N.A.
0
40
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
20
10
0
10
0
0
20
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
10
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
70
0
50
10
0
0
10
0
10
50
0
0
0
0
% E
% Phe:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
50
0
40
0
0
0
0
0
40
0
0
0
0
40
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
50
0
0
0
50
0
0
10
0
0
% K
% Leu:
0
0
10
0
0
0
10
0
0
0
0
10
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
10
40
0
0
0
30
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
10
0
0
40
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
10
0
10
10
10
0
10
20
0
50
10
0
% R
% Ser:
10
0
10
10
10
10
50
20
10
0
0
0
10
20
20
% S
% Thr:
0
0
10
0
10
0
0
0
10
0
0
10
0
0
30
% T
% Val:
10
0
0
0
0
10
0
0
0
0
0
10
0
0
0
% V
% Trp:
0
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
10
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _