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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP48 All Species: 23.64
Human Site: S396 Identified Species: 47.27
UniProt: Q86UV5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UV5 NP_001027902.1 1035 119032 S396 D L A E P S K S Q T R K P K C
Chimpanzee Pan troglodytes XP_001163789 1035 119073 S396 D L A E P S K S Q T R K P K C
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535372 1036 119247 S396 D L A E P S K S Q T R K P K C
Cat Felis silvestris
Mouse Mus musculus Q3V0C5 1052 120612 S395 E D L E P S K S Q T R K P K C
Rat Rattus norvegicus Q76LT8 1036 118768 S396 D L T E P S K S Q T R K P K C
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517111 632 72775 Y52 L P A G A E P Y E F V S L E W
Chicken Gallus gallus Q5ZM45 1033 118673 S394 D L A E P S K S Q T R K P K C
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001019581 514 59909
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393474 958 110839 E362 N I C N S N G E W Y Q F S D D
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188027 399 45880
Poplar Tree Populus trichocarpa XP_002306642 1084 121450 L430 D A V Q P Q S L E S N I H S C
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCJ9 1067 119915 S417 T D G I Q S G S S D C R S A I
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 98.5 N.A. 92.9 94.4 N.A. 52.5 87.3 N.A. 38.3 N.A. N.A. 25.7 N.A. 23.4
Protein Similarity: 100 100 N.A. 99.5 N.A. 95.7 97.3 N.A. 55.6 93 N.A. 44.4 N.A. N.A. 45.7 N.A. 30.7
P-Site Identity: 100 100 N.A. 100 N.A. 80 93.3 N.A. 6.6 100 N.A. 0 N.A. N.A. 0 N.A. 0
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 93.3 N.A. 20 100 N.A. 0 N.A. N.A. 26.6 N.A. 0
Percent
Protein Identity: 26.7 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 46.4 N.A. N.A.
P-Site Identity: 20 N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: 40 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 9 42 0 9 0 0 0 0 0 0 0 0 9 0 % A
% Cys: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 59 % C
% Asp: 50 17 0 0 0 0 0 0 0 9 0 0 0 9 9 % D
% Glu: 9 0 0 50 0 9 0 9 17 0 0 0 0 9 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 9 0 9 0 0 0 % F
% Gly: 0 0 9 9 0 0 17 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % H
% Ile: 0 9 0 9 0 0 0 0 0 0 0 9 0 0 9 % I
% Lys: 0 0 0 0 0 0 50 0 0 0 0 50 0 50 0 % K
% Leu: 9 42 9 0 0 0 0 9 0 0 0 0 9 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 9 0 0 9 0 9 0 0 0 0 9 0 0 0 0 % N
% Pro: 0 9 0 0 59 0 9 0 0 0 0 0 50 0 0 % P
% Gln: 0 0 0 9 9 9 0 0 50 0 9 0 0 0 0 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 50 9 0 0 0 % R
% Ser: 0 0 0 0 9 59 9 59 9 9 0 9 17 9 0 % S
% Thr: 9 0 9 0 0 0 0 0 0 50 0 0 0 0 0 % T
% Val: 0 0 9 0 0 0 0 0 0 0 9 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 9 0 0 0 0 0 9 % W
% Tyr: 0 0 0 0 0 0 0 9 0 9 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _