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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
USP48
All Species:
23.94
Human Site:
Y678
Identified Species:
47.88
UniProt:
Q86UV5
Number Species:
11
Phosphosite Substitution
Charge Score:
0.18
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UV5
NP_001027902.1
1035
119032
Y678
A
W
S
K
L
Q
Q
Y
F
P
K
A
P
E
F
Chimpanzee
Pan troglodytes
XP_001163789
1035
119073
Y678
A
W
S
K
L
Q
Q
Y
F
P
K
A
P
E
F
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_535372
1036
119247
Y679
A
W
S
K
L
Q
Q
Y
F
P
K
A
P
E
F
Cat
Felis silvestris
Mouse
Mus musculus
Q3V0C5
1052
120612
Y677
A
W
S
K
L
Q
Q
Y
F
P
K
A
P
E
F
Rat
Rattus norvegicus
Q76LT8
1036
118768
Y679
A
W
S
K
L
Q
Q
Y
F
P
K
A
P
E
F
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517111
632
72775
T306
L
S
S
W
P
Q
E
T
N
V
L
Y
I
V
S
Chicken
Gallus gallus
Q5ZM45
1033
118673
Y677
A
W
K
K
L
K
Q
Y
F
P
K
A
P
E
F
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001019581
514
59909
L188
S
K
L
F
L
S
L
L
E
D
T
L
S
K
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_393474
958
110839
N619
R
L
D
P
L
K
V
N
R
A
K
C
I
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188027
399
45880
S72
L
A
A
I
P
D
E
S
L
Q
P
T
S
I
C
Poplar Tree
Populus trichocarpa
XP_002306642
1084
121450
D716
A
V
A
V
K
S
D
D
P
L
G
C
T
T
F
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SCJ9
1067
119915
D705
A
L
K
V
M
S
E
D
T
L
D
C
T
C
F
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.8
N.A.
98.5
N.A.
92.9
94.4
N.A.
52.5
87.3
N.A.
38.3
N.A.
N.A.
25.7
N.A.
23.4
Protein Similarity:
100
100
N.A.
99.5
N.A.
95.7
97.3
N.A.
55.6
93
N.A.
44.4
N.A.
N.A.
45.7
N.A.
30.7
P-Site Identity:
100
100
N.A.
100
N.A.
100
100
N.A.
13.3
86.6
N.A.
6.6
N.A.
N.A.
13.3
N.A.
0
P-Site Similarity:
100
100
N.A.
100
N.A.
100
100
N.A.
20
93.3
N.A.
20
N.A.
N.A.
20
N.A.
13.3
Percent
Protein Identity:
26.7
N.A.
N.A.
27.2
N.A.
N.A.
Protein Similarity:
43.5
N.A.
N.A.
46.4
N.A.
N.A.
P-Site Identity:
13.3
N.A.
N.A.
13.3
N.A.
N.A.
P-Site Similarity:
20
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
67
9
17
0
0
0
0
0
0
9
0
50
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
25
0
9
9
% C
% Asp:
0
0
9
0
0
9
9
17
0
9
9
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
25
0
9
0
0
0
0
50
0
% E
% Phe:
0
0
0
9
0
0
0
0
50
0
0
0
0
0
67
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
9
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
9
0
0
0
0
0
0
0
0
17
9
9
% I
% Lys:
0
9
17
50
9
17
0
0
0
0
59
0
0
9
0
% K
% Leu:
17
17
9
0
67
0
9
9
9
17
9
9
0
0
0
% L
% Met:
0
0
0
0
9
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
9
0
0
0
0
0
0
% N
% Pro:
0
0
0
9
17
0
0
0
9
50
9
0
50
9
0
% P
% Gln:
0
0
0
0
0
50
50
0
0
9
0
0
0
0
9
% Q
% Arg:
9
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% R
% Ser:
9
9
50
0
0
25
0
9
0
0
0
0
17
0
9
% S
% Thr:
0
0
0
0
0
0
0
9
9
0
9
9
17
9
0
% T
% Val:
0
9
0
17
0
0
9
0
0
9
0
0
0
9
0
% V
% Trp:
0
50
0
9
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
50
0
0
0
9
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _