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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: USP48 All Species: 21.21
Human Site: Y927 Identified Species: 42.42
UniProt: Q86UV5 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UV5 NP_001027902.1 1035 119032 Y927 S H Q N Y I A Y Q K Q V I R R
Chimpanzee Pan troglodytes XP_001163789 1035 119073 Y927 S H Q N Y I A Y Q K Q V I R R
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_535372 1036 119247 Y928 T H Q N Y I A Y Q K Q V I R R
Cat Felis silvestris
Mouse Mus musculus Q3V0C5 1052 120612 Y944 S Q Q G Y V A Y Q K Q V I R R
Rat Rattus norvegicus Q76LT8 1036 118768 Y928 S Q Q G Y V A Y Q K Q V I R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001517111 632 72775 I529 L V Y Q K Q V I R R S T R H R
Chicken Gallus gallus Q5ZM45 1033 118673 Y925 S H Q S Y I S Y Q K Q G I R R
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001019581 514 59909 L411 C S R N A Y M L V Y K Q Q T E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_393474 958 110839 L848 A R V E Q E R L E S L K Y D R
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188027 399 45880 G296 V A H I R S H G D G G V W F K
Poplar Tree Populus trichocarpa XP_002306642 1084 121450 E966 E A S S T T P E T D R R A S K
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9SCJ9 1067 119915 E949 E A S D S S F E V D R R T S K
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.8 N.A. 98.5 N.A. 92.9 94.4 N.A. 52.5 87.3 N.A. 38.3 N.A. N.A. 25.7 N.A. 23.4
Protein Similarity: 100 100 N.A. 99.5 N.A. 95.7 97.3 N.A. 55.6 93 N.A. 44.4 N.A. N.A. 45.7 N.A. 30.7
P-Site Identity: 100 100 N.A. 93.3 N.A. 80 80 N.A. 6.6 80 N.A. 6.6 N.A. N.A. 6.6 N.A. 6.6
P-Site Similarity: 100 100 N.A. 100 N.A. 86.6 86.6 N.A. 20 93.3 N.A. 20 N.A. N.A. 20 N.A. 13.3
Percent
Protein Identity: 26.7 N.A. N.A. 27.2 N.A. N.A.
Protein Similarity: 43.5 N.A. N.A. 46.4 N.A. N.A.
P-Site Identity: 0 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 20 N.A. N.A. 20 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 25 0 0 9 0 42 0 0 0 0 0 9 0 0 % A
% Cys: 9 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 9 0 0 0 0 9 17 0 0 0 9 0 % D
% Glu: 17 0 0 9 0 9 0 17 9 0 0 0 0 0 9 % E
% Phe: 0 0 0 0 0 0 9 0 0 0 0 0 0 9 0 % F
% Gly: 0 0 0 17 0 0 0 9 0 9 9 9 0 0 0 % G
% His: 0 34 9 0 0 0 9 0 0 0 0 0 0 9 0 % H
% Ile: 0 0 0 9 0 34 0 9 0 0 0 0 50 0 0 % I
% Lys: 0 0 0 0 9 0 0 0 0 50 9 9 0 0 25 % K
% Leu: 9 0 0 0 0 0 0 17 0 0 9 0 0 0 0 % L
% Met: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 34 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 9 0 0 0 0 0 0 0 0 % P
% Gln: 0 17 50 9 9 9 0 0 50 0 50 9 9 0 0 % Q
% Arg: 0 9 9 0 9 0 9 0 9 9 17 17 9 50 67 % R
% Ser: 42 9 17 17 9 17 9 0 0 9 9 0 0 17 0 % S
% Thr: 9 0 0 0 9 9 0 0 9 0 0 9 9 9 0 % T
% Val: 9 9 9 0 0 17 9 0 17 0 0 50 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % W
% Tyr: 0 0 9 0 50 9 0 50 0 9 0 0 9 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _