KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRIM74
All Species:
13.94
Human Site:
S116
Identified Species:
43.81
UniProt:
Q86UV6
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.14
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UV6
NP_942150.1
250
28547
S116
G
L
C
G
L
L
G
S
H
Q
H
H
P
V
T
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Q0PF16
497
57280
Q138
F
L
M
E
E
V
A
Q
E
Y
H
V
K
L
Q
Dog
Lupus familis
XP_546929
487
55202
S116
G
L
C
G
L
L
G
S
H
Q
H
H
R
V
T
Cat
Felis silvestris
Mouse
Mus musculus
Q810I2
483
54589
S116
G
L
C
G
L
L
G
S
H
Q
H
H
R
V
T
Rat
Rattus norvegicus
Q810I1
483
54701
S116
G
L
C
G
L
L
G
S
H
Q
H
H
R
V
T
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_415709
492
55730
N118
G
L
C
G
T
I
G
N
H
K
Q
H
K
I
T
Frog
Xenopus laevis
Q6PGR9
477
54096
K115
G
V
C
A
S
L
G
K
H
K
G
H
N
I
I
Zebra Danio
Brachydanio rerio
NP_001103174
477
54442
T147
P
F
C
K
D
E
L
T
M
K
I
K
I
L
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
20.1
43.1
N.A.
41.4
42
N.A.
N.A.
29
21.5
22.6
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
N.A.
32.1
46.4
N.A.
45.7
45.7
N.A.
N.A.
39.6
34.3
34.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
N.A.
13.3
93.3
N.A.
93.3
93.3
N.A.
N.A.
53.3
40
6.6
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
N.A.
26.6
93.3
N.A.
93.3
93.3
N.A.
N.A.
80
60
26.6
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
13
0
0
13
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
88
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
13
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
13
13
13
0
0
13
0
0
0
0
0
13
% E
% Phe:
13
13
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
75
0
0
63
0
0
75
0
0
0
13
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
75
0
63
75
0
0
0
% H
% Ile:
0
0
0
0
0
13
0
0
0
0
13
0
13
25
13
% I
% Lys:
0
0
0
13
0
0
0
13
0
38
0
13
25
0
0
% K
% Leu:
0
75
0
0
50
63
13
0
0
0
0
0
0
25
0
% L
% Met:
0
0
13
0
0
0
0
0
13
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
13
0
0
0
0
13
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
0
0
0
0
13
0
0
% P
% Gln:
0
0
0
0
0
0
0
13
0
50
13
0
0
0
13
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
38
0
0
% R
% Ser:
0
0
0
0
13
0
0
50
0
0
0
0
0
0
0
% S
% Thr:
0
0
0
0
13
0
0
13
0
0
0
0
0
0
63
% T
% Val:
0
13
0
0
0
13
0
0
0
0
0
13
0
50
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
13
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _