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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CADPS2 All Species: 35.45
Human Site: T819 Identified Species: 78
UniProt: Q86UW7 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UW7 NP_001009571.2 1296 147735 T819 L I N Y T R L T E Y A K I E E
Chimpanzee Pan troglodytes XP_001146490 1296 147661 T819 L I N Y T R L T E Y A K I E E
Rhesus Macaque Macaca mulatta XP_001084178 1297 147885 T820 L I N Y T R L T E Y A K I E E
Dog Lupus familis XP_532534 1204 137239 Q761 E L C I E V L Q Q N E E H H A
Cat Felis silvestris
Mouse Mus musculus Q8BYR5 1297 147822 T820 L I N Y T R L T E Y A K I E E
Rat Rattus norvegicus Q62717 1289 146248 S852 L V N Y S R L S E Y A K I E E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507532 1359 153617 T875 L I N Y T R L T E Y A K I E G
Chicken Gallus gallus XP_001233823 1325 150564 S830 L V N Y T R L S E Y A K I E E
Frog Xenopus laevis Q6GLR7 1299 148702 S821 L V N Y T R L S E Y A K I E E
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9NHE5 1436 162680 S904 L V N Y T R L S N K A K I D E
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q23658 1396 159184 C955 L V N Y T R I C N E A K I E Q
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.6 99.3 88.4 N.A. 95.9 77 N.A. 85.3 77.6 77.1 N.A. N.A. 53.7 N.A. 44.7 N.A.
Protein Similarity: 100 100 99.4 90.4 N.A. 98.1 86.7 N.A. 90.1 87.6 87.7 N.A. N.A. 68.8 N.A. 63.3 N.A.
P-Site Identity: 100 100 100 6.6 N.A. 100 80 N.A. 93.3 86.6 86.6 N.A. N.A. 66.6 N.A. 60 N.A.
P-Site Similarity: 100 100 100 26.6 N.A. 100 100 N.A. 93.3 100 100 N.A. N.A. 86.6 N.A. 80 N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 91 0 0 0 10 % A
% Cys: 0 0 10 0 0 0 0 10 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % D
% Glu: 10 0 0 0 10 0 0 0 73 10 10 10 0 82 73 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 10 10 0 % H
% Ile: 0 46 0 10 0 0 10 0 0 0 0 0 91 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 10 0 91 0 0 0 % K
% Leu: 91 10 0 0 0 0 91 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 91 0 0 0 0 0 19 10 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 10 10 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 0 91 0 0 0 0 0 0 0 0 0 % R
% Ser: 0 0 0 0 10 0 0 37 0 0 0 0 0 0 0 % S
% Thr: 0 0 0 0 82 0 0 46 0 0 0 0 0 0 0 % T
% Val: 0 46 0 0 0 10 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 91 0 0 0 0 0 73 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _