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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DTX2 All Species: 28.48
Human Site: Y476 Identified Species: 56.97
UniProt: Q86UW9 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UW9 NP_001096064.1 622 67246 Y476 C P S C K T I Y G E K T G T Q
Chimpanzee Pan troglodytes XP_001157724 626 67539 P471 T D S K A I G P L A V G R L T
Rhesus Macaque Macaca mulatta XP_001088765 736 78221 Y588 C P T C K T I Y G V K T G T Q
Dog Lupus familis XP_536849 621 67018 Y475 C P S C K T I Y G E K T G T Q
Cat Felis silvestris
Mouse Mus musculus Q8R3P2 619 67177 Y473 C P S C K T I Y G E K T G T Q
Rat Rattus norvegicus NP_001100627 619 67227 Y473 C P S C K T I Y G E K T G T Q
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507953 495 53348 E363 T Q P P G K M E F H L I P H A
Chicken Gallus gallus XP_415763 577 62810 E445 T Q P K G K M E V S T F P Q S
Frog Xenopus laevis Q8AW93 623 68315 Y477 C P T C K A I Y G E K T G T Q
Zebra Danio Brachydanio rerio NP_001120779 566 61244 S434 E I Y S I P Q S L P G H P D C
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q23985 738 82168 Y604 C P V C G I V Y G E K V G N Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_798685 627 67745 Y481 C P T C K A I Y G V K C G N Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 86 38.4 91.1 N.A. 84.8 85.2 N.A. 39.3 57.5 45.7 52 N.A. 27.1 N.A. N.A. 33.9
Protein Similarity: 100 88.9 50.6 93.7 N.A. 89 89 N.A. 49 67.1 58.7 62 N.A. 40.3 N.A. N.A. 47.8
P-Site Identity: 100 6.6 86.6 100 N.A. 100 100 N.A. 0 0 86.6 0 N.A. 60 N.A. N.A. 66.6
P-Site Similarity: 100 6.6 93.3 100 N.A. 100 100 N.A. 6.6 6.6 93.3 0 N.A. 66.6 N.A. N.A. 73.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 9 17 0 0 0 9 0 0 0 0 9 % A
% Cys: 67 0 0 67 0 0 0 0 0 0 0 9 0 0 9 % C
% Asp: 0 9 0 0 0 0 0 0 0 0 0 0 0 9 0 % D
% Glu: 9 0 0 0 0 0 0 17 0 50 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 9 0 0 9 0 0 0 % F
% Gly: 0 0 0 0 25 0 9 0 67 0 9 9 67 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 9 0 9 0 9 0 % H
% Ile: 0 9 0 0 9 17 59 0 0 0 0 9 0 0 0 % I
% Lys: 0 0 0 17 59 17 0 0 0 0 67 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 0 0 17 0 9 0 0 9 0 % L
% Met: 0 0 0 0 0 0 17 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % N
% Pro: 0 67 17 9 0 9 0 9 0 9 0 0 25 0 0 % P
% Gln: 0 17 0 0 0 0 9 0 0 0 0 0 0 9 67 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 0 9 0 0 % R
% Ser: 0 0 42 9 0 0 0 9 0 9 0 0 0 0 9 % S
% Thr: 25 0 25 0 0 42 0 0 0 0 9 50 0 50 9 % T
% Val: 0 0 9 0 0 0 9 0 9 17 9 9 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 9 0 0 0 0 67 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _