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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM83A All Species: 20.3
Human Site: Y404 Identified Species: 49.63
UniProt: Q86UY5 Number Species: 9
    Phosphosite Substitution
    Charge Score: -0.22
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86UY5 NP_116288.2 434 47458 Y404 V Y S N L G A Y R P T R L Q L
Chimpanzee Pan troglodytes XP_001147027 434 47418 Y404 V Y S N L G A Y R P T R L Q L
Rhesus Macaque Macaca mulatta XP_001099761 434 47657 Y404 V Y S N L G A Y R P T R L Q L
Dog Lupus familis XP_851601 392 42797 R363 Y S N L N A Y R P T R L Q L E
Cat Felis silvestris
Mouse Mus musculus Q8K2P2 436 48174 Y406 P Y S S L M A Y R P T R L Q L
Rat Rattus norvegicus NP_001124048 436 48260 Y406 P Y S S L M A Y R P T R L Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001506192 427 47555 R396 Y S Q L N V Y R T Q R T C L P
Chicken Gallus gallus XP_001233861 470 53107 Y441 L Y N N M N I Y R P V R V R Q
Frog Xenopus laevis Q6PF42 443 50454 I414 F F N N N A N I Y R S F R M R
Zebra Danio Brachydanio rerio XP_001340276 405 46003 F376 V T S Q S P L F K D Y N A R S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99 96 71.1 N.A. 81.8 80.9 N.A. 55.5 51.7 51.6 37 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 99.3 96.7 77.1 N.A. 87.1 86.6 N.A. 65.6 63.4 66.3 52.5 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 80 80 N.A. 0 40 6.6 13.3 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 86.6 86.6 N.A. 0 73.3 26.6 33.3 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 20 50 0 0 0 0 0 10 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 10 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 10 % E
% Phe: 10 10 0 0 0 0 0 10 0 0 0 10 0 0 0 % F
% Gly: 0 0 0 0 0 30 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 10 0 0 0 0 0 0 % K
% Leu: 10 0 0 20 50 0 10 0 0 0 0 10 50 20 50 % L
% Met: 0 0 0 0 10 20 0 0 0 0 0 0 0 10 0 % M
% Asn: 0 0 30 50 30 10 10 0 0 0 0 10 0 0 0 % N
% Pro: 20 0 0 0 0 10 0 0 10 60 0 0 0 0 10 % P
% Gln: 0 0 10 10 0 0 0 0 0 10 0 0 10 50 10 % Q
% Arg: 0 0 0 0 0 0 0 20 60 10 20 60 10 20 10 % R
% Ser: 0 20 60 20 10 0 0 0 0 0 10 0 0 0 10 % S
% Thr: 0 10 0 0 0 0 0 0 10 10 50 10 0 0 0 % T
% Val: 40 0 0 0 0 10 0 0 0 0 10 0 10 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 20 60 0 0 0 0 20 60 10 0 10 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _