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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NT5DC3
All Species:
9.7
Human Site:
S253
Identified Species:
23.7
UniProt:
Q86UY8
Number Species:
9
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86UY8
NP_001026871.1
548
63420
S253
L
Y
K
D
V
K
D
S
I
R
D
V
H
I
K
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001087752
491
57820
T242
G
K
K
M
F
L
I
T
N
S
P
S
S
F
V
Dog
Lupus familis
XP_855053
550
63077
I261
K
G
I
M
Y
R
A
I
E
A
D
I
E
K
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q3UHB1
546
63152
S251
L
Y
K
D
V
K
D
S
I
R
D
V
H
I
K
Rat
Rattus norvegicus
Q6Q0N3
553
63634
R257
K
D
V
T
D
A
I
R
D
V
H
V
K
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506043
915
103398
K619
K
D
I
T
D
A
I
K
D
V
H
V
K
G
M
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GN91
499
58768
S249
K
M
F
L
I
T
N
S
P
S
S
F
V
N
K
Zebra Danio
Brachydanio rerio
XP_686778
576
67497
V278
L
Y
K
D
V
K
E
V
I
G
N
V
H
V
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_610499
548
63580
R268
E
I
V
F
H
D
T
R
T
A
M
G
S
C
H
Honey Bee
Apis mellifera
XP_393672
528
62275
S250
L
F
R
D
V
K
N
S
V
Q
S
C
H
P
I
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
88.5
91
N.A.
91.9
61.2
N.A.
39.4
N.A.
73.7
69.2
N.A.
43.4
42.1
N.A.
N.A.
Protein Similarity:
100
N.A.
88.6
93.6
N.A.
94.3
78.8
N.A.
50
N.A.
82.6
79.8
N.A.
62.4
59.8
N.A.
N.A.
P-Site Identity:
100
N.A.
6.6
6.6
N.A.
100
6.6
N.A.
6.6
N.A.
13.3
60
N.A.
0
40
N.A.
N.A.
P-Site Similarity:
100
N.A.
13.3
20
N.A.
100
6.6
N.A.
6.6
N.A.
26.6
86.6
N.A.
0
73.3
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
20
10
0
0
20
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
10
0
10
0
% C
% Asp:
0
20
0
40
20
10
20
0
20
0
30
0
0
0
0
% D
% Glu:
10
0
0
0
0
0
10
0
10
0
0
0
10
0
0
% E
% Phe:
0
10
10
10
10
0
0
0
0
0
0
10
0
10
0
% F
% Gly:
10
10
0
0
0
0
0
0
0
10
0
10
0
20
0
% G
% His:
0
0
0
0
10
0
0
0
0
0
20
0
40
0
10
% H
% Ile:
0
10
20
0
10
0
30
10
30
0
0
10
0
20
10
% I
% Lys:
40
10
40
0
0
40
0
10
0
0
0
0
20
10
30
% K
% Leu:
40
0
0
10
0
10
0
0
0
0
0
0
0
0
10
% L
% Met:
0
10
0
20
0
0
0
0
0
0
10
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
20
0
10
0
10
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
10
0
10
0
0
10
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% Q
% Arg:
0
0
10
0
0
10
0
20
0
20
0
0
0
0
10
% R
% Ser:
0
0
0
0
0
0
0
40
0
20
20
10
20
0
0
% S
% Thr:
0
0
0
20
0
10
10
10
10
0
0
0
0
0
0
% T
% Val:
0
0
20
0
40
0
0
10
10
20
0
50
10
10
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
30
0
0
10
0
0
0
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _