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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: CASZ1 All Species: 23.94
Human Site: Y661 Identified Species: 52.67
UniProt: Q86V15 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86V15 NP_001073312.1 1759 190148 Y661 C K Y E G C V Y S K A T N H F
Chimpanzee Pan troglodytes XP_514369 1706 184920 S643 S S K N S S L S A S P T S Q Q
Rhesus Macaque Macaca mulatta XP_001118792 1895 204675 Y644 C K Y E G C V Y S K A T N H F
Dog Lupus familis XP_544573 1182 126261 L212 D Q N T R D E L A R K I S F E
Cat Felis silvestris
Mouse Mus musculus Q9CWL2 1761 191169 Y660 C K Y E G C M Y S K A T N H F
Rat Rattus norvegicus XP_002729610 1789 194321 Y683 C K Y E G C V Y S K A T N H F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510284 1104 121776 V134 V Y T S T S D V M T H E N F H
Chicken Gallus gallus XP_417611 1825 198566 Y678 C K Y E G C V Y S K A T N H F
Frog Xenopus laevis NP_001104226 1108 121553 V138 T E I P P E G V Y M V Q P K G
Zebra Danio Brachydanio rerio XP_001923862 1760 194746 Y680 C K Y E G C V Y S K A T N H F
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_394008 1528 170711 Q558 A I I Q E G F Q R F R A T E S
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 78.5 83.5 60.1 N.A. 90 89.3 N.A. 50.7 69.4 43.1 61.8 N.A. N.A. 21.8 N.A. N.A.
Protein Similarity: 100 82.2 84.9 61.5 N.A. 93.1 92.2 N.A. 54.5 78 49.5 72 N.A. N.A. 35.3 N.A. N.A.
P-Site Identity: 100 6.6 100 0 N.A. 93.3 100 N.A. 6.6 100 0 100 N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 26.6 100 26.6 N.A. 100 100 N.A. 6.6 100 6.6 100 N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 10 0 0 0 0 0 0 0 19 0 55 10 0 0 0 % A
% Cys: 55 0 0 0 0 55 0 0 0 0 0 0 0 0 0 % C
% Asp: 10 0 0 0 0 10 10 0 0 0 0 0 0 0 0 % D
% Glu: 0 10 0 55 10 10 10 0 0 0 0 10 0 10 10 % E
% Phe: 0 0 0 0 0 0 10 0 0 10 0 0 0 19 55 % F
% Gly: 0 0 0 0 55 10 10 0 0 0 0 0 0 0 10 % G
% His: 0 0 0 0 0 0 0 0 0 0 10 0 0 55 10 % H
% Ile: 0 10 19 0 0 0 0 0 0 0 0 10 0 0 0 % I
% Lys: 0 55 10 0 0 0 0 0 0 55 10 0 0 10 0 % K
% Leu: 0 0 0 0 0 0 10 10 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 10 0 10 10 0 0 0 0 0 % M
% Asn: 0 0 10 10 0 0 0 0 0 0 0 0 64 0 0 % N
% Pro: 0 0 0 10 10 0 0 0 0 0 10 0 10 0 0 % P
% Gln: 0 10 0 10 0 0 0 10 0 0 0 10 0 10 10 % Q
% Arg: 0 0 0 0 10 0 0 0 10 10 10 0 0 0 0 % R
% Ser: 10 10 0 10 10 19 0 10 55 10 0 0 19 0 10 % S
% Thr: 10 0 10 10 10 0 0 0 0 10 0 64 10 0 0 % T
% Val: 10 0 0 0 0 0 46 19 0 0 10 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 10 55 0 0 0 0 55 10 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _