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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM35A
All Species:
12.12
Human Site:
S216
Identified Species:
44.44
UniProt:
Q86V20
Number Species:
6
Phosphosite Substitution
Charge Score:
0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86V20
NP_061927.2
835
93705
S216
Q
C
L
G
L
F
S
S
N
A
V
D
K
S
R
Chimpanzee
Pan troglodytes
XP_507895
904
101663
S216
Q
C
L
G
L
F
S
S
N
A
V
D
K
S
R
Rhesus Macaque
Macaca mulatta
XP_001082677
836
93490
S217
Q
C
L
G
L
F
S
S
N
A
V
Y
K
P
R
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q3UEN2
898
99820
S205
R
Q
S
Q
E
S
F
S
D
T
R
C
E
P
Q
Rat
Rattus norvegicus
NP_001020199
911
101838
S210
Q
S
Q
E
S
F
A
S
D
T
Q
C
E
P
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001517739
830
91680
C210
H
R
E
T
L
S
H
C
L
R
L
F
F
P
E
Chicken
Gallus gallus
XP_421498
619
70553
D17
K
P
N
G
E
L
S
D
C
P
D
L
V
V
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
91
93.3
N.A.
N.A.
58.6
57.6
N.A.
45.2
38
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
92
96.1
N.A.
N.A.
70.8
70.4
N.A.
62.6
53.5
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
86.6
N.A.
N.A.
6.6
20
N.A.
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
86.6
N.A.
N.A.
33.3
46.6
N.A.
13.3
20
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
15
0
0
43
0
0
0
0
0
% A
% Cys:
0
43
0
0
0
0
0
15
15
0
0
29
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
15
29
0
15
29
0
0
0
% D
% Glu:
0
0
15
15
29
0
0
0
0
0
0
0
29
0
15
% E
% Phe:
0
0
0
0
0
58
15
0
0
0
0
15
15
0
0
% F
% Gly:
0
0
0
58
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
15
0
0
0
0
0
15
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
15
0
0
0
0
0
0
0
0
0
0
0
43
0
0
% K
% Leu:
0
0
43
0
58
15
0
0
15
0
15
15
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
15
0
0
0
0
0
43
0
0
0
0
0
0
% N
% Pro:
0
15
0
0
0
0
0
0
0
15
0
0
0
58
0
% P
% Gln:
58
15
15
15
0
0
0
0
0
0
15
0
0
0
29
% Q
% Arg:
15
15
0
0
0
0
0
0
0
15
15
0
0
0
43
% R
% Ser:
0
15
15
0
15
29
58
72
0
0
0
0
0
29
15
% S
% Thr:
0
0
0
15
0
0
0
0
0
29
0
0
0
0
0
% T
% Val:
0
0
0
0
0
0
0
0
0
0
43
0
15
15
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
15
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _