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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AACS
All Species:
36.36
Human Site:
Y663
Identified Species:
88.89
UniProt:
Q86V21
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86V21
NP_076417.2
672
75144
Y663
N
P
E
T
L
D
L
Y
R
D
I
P
E
L
Q
Chimpanzee
Pan troglodytes
XP_001135709
684
76661
Y675
N
P
E
T
L
D
L
Y
R
D
I
P
E
L
Q
Rhesus Macaque
Macaca mulatta
XP_001103579
672
75075
Y663
N
P
E
T
L
D
L
Y
R
D
I
P
E
L
Q
Dog
Lupus familis
XP_543365
780
87041
Y771
N
P
E
T
L
D
L
Y
Q
N
I
P
E
L
Q
Cat
Felis silvestris
Mouse
Mus musculus
Q9D2R0
672
75182
Y663
N
P
E
T
L
D
L
Y
R
D
I
P
E
L
Q
Rat
Rattus norvegicus
Q9JMI1
672
75021
Y663
N
P
E
S
L
D
L
Y
R
D
I
P
E
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q5ZLG0
667
74352
Y658
N
P
E
T
L
D
L
Y
Q
N
I
P
E
L
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
A3QK15
673
74948
Y664
N
P
D
S
L
D
L
Y
K
N
L
P
E
L
Q
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21166
700
78321
I686
A
V
Q
K
A
S
S
I
R
N
P
E
S
L
D
Sea Urchin
Strong. purpuratus
XP_795289
684
76159
Y636
N
P
D
S
L
D
L
Y
Q
D
I
P
E
L
Q
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.3
98.2
75.3
N.A.
89.8
89.2
N.A.
N.A.
85.4
N.A.
77.7
N.A.
N.A.
N.A.
36.7
65.3
Protein Similarity:
100
96
99.1
81
N.A.
95.3
94.9
N.A.
N.A.
93.3
N.A.
87.8
N.A.
N.A.
N.A.
56.4
78.9
P-Site Identity:
100
100
100
86.6
N.A.
100
93.3
N.A.
N.A.
86.6
N.A.
66.6
N.A.
N.A.
N.A.
13.3
80
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
N.A.
100
N.A.
100
N.A.
N.A.
N.A.
26.6
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
0
0
0
10
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
20
0
0
90
0
0
0
60
0
0
0
0
10
% D
% Glu:
0
0
70
0
0
0
0
0
0
0
0
10
90
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
80
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
0
0
0
90
0
90
0
0
0
10
0
0
100
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
90
0
0
0
0
0
0
0
0
40
0
0
0
0
0
% N
% Pro:
0
90
0
0
0
0
0
0
0
0
10
90
0
0
0
% P
% Gln:
0
0
10
0
0
0
0
0
30
0
0
0
0
0
90
% Q
% Arg:
0
0
0
0
0
0
0
0
60
0
0
0
0
0
0
% R
% Ser:
0
0
0
30
0
10
10
0
0
0
0
0
10
0
0
% S
% Thr:
0
0
0
60
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
10
0
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
90
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _