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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
VASH2
All Species:
27.27
Human Site:
Y251
Identified Species:
66.67
UniProt:
Q86V25
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86V25
NP_001129946.1
355
40450
Y251
K
K
V
K
I
G
L
Y
V
P
H
E
P
H
S
Chimpanzee
Pan troglodytes
XP_001170898
355
40431
Y251
K
K
V
K
I
G
L
Y
V
P
H
E
P
H
S
Rhesus Macaque
Macaca mulatta
XP_001107184
355
40447
Y251
K
K
V
K
I
G
L
Y
V
P
H
E
P
H
S
Dog
Lupus familis
XP_849157
355
40403
Y251
K
K
V
K
I
G
L
Y
V
P
H
E
P
H
S
Cat
Felis silvestris
Mouse
Mus musculus
Q8C5G2
355
40524
Y251
K
K
V
K
I
G
L
Y
V
P
H
E
P
H
S
Rat
Rattus norvegicus
XP_578575
380
42134
C277
K
K
V
K
L
G
Q
C
V
S
H
D
P
H
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510897
355
40366
Y251
K
K
V
K
I
G
L
Y
V
P
H
E
P
H
S
Chicken
Gallus gallus
XP_419424
254
29751
Y151
K
K
V
K
I
G
L
Y
V
P
H
E
P
H
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001020694
348
39579
D244
T
L
S
E
L
V
F
D
F
E
D
S
Y
R
R
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783118
269
30419
W166
H
S
F
E
Q
I
H
W
R
H
L
S
L
N
M
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
100
99.4
98.8
N.A.
97.1
51.8
N.A.
88.4
62.5
N.A.
63.9
N.A.
N.A.
N.A.
N.A.
40
Protein Similarity:
100
100
99.7
99.4
N.A.
98.3
67.6
N.A.
94.3
67.6
N.A.
76.9
N.A.
N.A.
N.A.
N.A.
51.5
P-Site Identity:
100
100
100
100
N.A.
100
66.6
N.A.
100
100
N.A.
0
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
100
100
100
N.A.
100
80
N.A.
100
100
N.A.
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
10
0
0
10
10
0
0
0
% D
% Glu:
0
0
0
20
0
0
0
0
0
10
0
70
0
0
0
% E
% Phe:
0
0
10
0
0
0
10
0
10
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
80
0
0
0
0
0
0
0
0
0
% G
% His:
10
0
0
0
0
0
10
0
0
10
80
0
0
80
0
% H
% Ile:
0
0
0
0
70
10
0
0
0
0
0
0
0
0
0
% I
% Lys:
80
80
0
80
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
10
0
0
20
0
70
0
0
0
10
0
10
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
70
0
0
80
0
0
% P
% Gln:
0
0
0
0
10
0
10
0
0
0
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
10
0
0
0
0
10
10
% R
% Ser:
0
10
10
0
0
0
0
0
0
10
0
20
0
0
80
% S
% Thr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
80
0
0
10
0
0
80
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
70
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _