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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
FAM124A
All Species:
12.12
Human Site:
S451
Identified Species:
33.33
UniProt:
Q86V42
Number Species:
8
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86V42
NP_659456.2
546
60104
S451
P
L
P
S
E
R
C
S
S
H
W
A
A
H
K
Chimpanzee
Pan troglodytes
XP_001151637
542
60261
S447
P
I
P
S
E
R
C
S
S
H
W
A
A
H
K
Rhesus Macaque
Macaca mulatta
XP_001105422
546
59981
S451
P
L
P
S
E
R
C
S
S
H
W
A
A
H
K
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
Q8BLQ0
456
52061
K361
L
R
E
D
G
F
E
K
L
E
A
E
T
N
V
Rat
Rattus norvegicus
XP_002725164
525
57806
S430
S
L
S
S
E
G
C
S
S
R
W
P
A
H
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510071
438
48829
H344
Q
R
D
R
S
S
L
H
L
G
S
A
R
L
K
Chicken
Gallus gallus
Frog
Xenopus laevis
Q6GQ34
520
59016
L421
D
V
D
T
G
M
K
L
S
S
S
D
L
S
V
Zebra Danio
Brachydanio rerio
XP_001922375
527
59391
P431
Y
T
Q
P
K
L
R
P
H
L
K
A
P
A
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001188911
328
37989
F234
V
R
P
L
Y
T
S
F
L
Q
F
K
V
R
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
94.5
96.6
N.A.
N.A.
28.9
69.2
N.A.
29.8
N.A.
51.2
36
N.A.
N.A.
N.A.
N.A.
26
Protein Similarity:
100
94.8
98.3
N.A.
N.A.
44.5
76.5
N.A.
44.5
N.A.
64
49
N.A.
N.A.
N.A.
N.A.
38.1
P-Site Identity:
100
93.3
100
N.A.
N.A.
0
66.6
N.A.
13.3
N.A.
6.6
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
100
100
N.A.
N.A.
6.6
66.6
N.A.
13.3
N.A.
20
13.3
N.A.
N.A.
N.A.
N.A.
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
12
56
45
12
0
% A
% Cys:
0
0
0
0
0
0
45
0
0
0
0
0
0
0
0
% C
% Asp:
12
0
23
12
0
0
0
0
0
0
0
12
0
0
0
% D
% Glu:
0
0
12
0
45
0
12
0
0
12
0
12
0
0
12
% E
% Phe:
0
0
0
0
0
12
0
12
0
0
12
0
0
0
0
% F
% Gly:
0
0
0
0
23
12
0
0
0
12
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
12
12
34
0
0
0
45
0
% H
% Ile:
0
12
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
12
0
12
12
0
0
12
12
0
0
56
% K
% Leu:
12
34
0
12
0
12
12
12
34
12
0
0
12
12
0
% L
% Met:
0
0
0
0
0
12
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
12
0
% N
% Pro:
34
0
45
12
0
0
0
12
0
0
0
12
12
0
12
% P
% Gln:
12
0
12
0
0
0
0
0
0
12
0
0
0
0
0
% Q
% Arg:
0
34
0
12
0
34
12
0
0
12
0
0
12
12
0
% R
% Ser:
12
0
12
45
12
12
12
45
56
12
23
0
0
12
0
% S
% Thr:
0
12
0
12
0
12
0
0
0
0
0
0
12
0
0
% T
% Val:
12
12
0
0
0
0
0
0
0
0
0
0
12
0
23
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
45
0
0
0
0
% W
% Tyr:
12
0
0
0
12
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _