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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: FAM124A All Species: 7.88
Human Site: Y180 Identified Species: 21.67
UniProt: Q86V42 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86V42 NP_659456.2 546 60104 Y180 R F T V Y C R Y D N Y A D S L
Chimpanzee Pan troglodytes XP_001151637 542 60261 Y176 R F T V Y C R Y D N Y A D S L
Rhesus Macaque Macaca mulatta XP_001105422 546 59981 H180 R F T V Y C R H D N Y A D S L
Dog Lupus familis
Cat Felis silvestris
Mouse Mus musculus Q8BLQ0 456 52061 P111 G R S C S Y L P A N Q E F Y S
Rat Rattus norvegicus XP_002725164 525 57806 H167 R F T I Y C R H N S Y A D S L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001510071 438 48829 W94 D S F R H P P W K H H Q T R S
Chicken Gallus gallus
Frog Xenopus laevis Q6GQ34 520 59016 I168 Q V H Y G K E I I R F T I Y C
Zebra Danio Brachydanio rerio XP_001922375 527 59391 Y153 R F T V Y C H Y E T Y T E Q V
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001188911 328 37989
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.5 96.6 N.A. N.A. 28.9 69.2 N.A. 29.8 N.A. 51.2 36 N.A. N.A. N.A. N.A. 26
Protein Similarity: 100 94.8 98.3 N.A. N.A. 44.5 76.5 N.A. 44.5 N.A. 64 49 N.A. N.A. N.A. N.A. 38.1
P-Site Identity: 100 100 93.3 N.A. N.A. 6.6 73.3 N.A. 0 N.A. 0 53.3 N.A. N.A. N.A. N.A. 0
P-Site Similarity: 100 100 100 N.A. N.A. 13.3 100 N.A. 26.6 N.A. 13.3 73.3 N.A. N.A. N.A. N.A. 0
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 12 0 0 45 0 0 0 % A
% Cys: 0 0 0 12 0 56 0 0 0 0 0 0 0 0 12 % C
% Asp: 12 0 0 0 0 0 0 0 34 0 0 0 45 0 0 % D
% Glu: 0 0 0 0 0 0 12 0 12 0 0 12 12 0 0 % E
% Phe: 0 56 12 0 0 0 0 0 0 0 12 0 12 0 0 % F
% Gly: 12 0 0 0 12 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 12 0 12 0 12 23 0 12 12 0 0 0 0 % H
% Ile: 0 0 0 12 0 0 0 12 12 0 0 0 12 0 0 % I
% Lys: 0 0 0 0 0 12 0 0 12 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 0 0 12 0 0 0 0 0 0 0 45 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 12 45 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 12 12 12 0 0 0 0 0 0 0 % P
% Gln: 12 0 0 0 0 0 0 0 0 0 12 12 0 12 0 % Q
% Arg: 56 12 0 12 0 0 45 0 0 12 0 0 0 12 0 % R
% Ser: 0 12 12 0 12 0 0 0 0 12 0 0 0 45 23 % S
% Thr: 0 0 56 0 0 0 0 0 0 12 0 23 12 0 0 % T
% Val: 0 12 0 45 0 0 0 0 0 0 0 0 0 0 12 % V
% Trp: 0 0 0 0 0 0 0 12 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 12 56 12 0 34 0 0 56 0 0 23 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _