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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: MDP1 All Species: 1.21
Human Site: S99 Identified Species: 3.33
UniProt: Q86V88 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86V88 NP_612485.2 176 20109 S99 H R E I Y P G S K I T H F E R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_537388 217 24007 A120 D L D V P V A A A S R T G E I
Cat Felis silvestris
Mouse Mus musculus Q9D967 164 18564 Y89 E L F D L G K Y F I Q R E I Y
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509928 73 8172
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_001119991 139 16452 N64 Q G A K Q L L N L F N W D N Y
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa XP_002323938 190 21640 H102 E I F A S W T H K T D H F Q R
Maize Zea mays NP_001132732 173 19828 S98 F V A Q E I F S S W T H K T E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana NP_179027 190 21730 H102 E I Y S S W S H K T E H F Q K
Baker's Yeast Sacchar. cerevisiae P40081 178 20423 A101 A G V V T P L A N L F D E F Q
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. N.A. 66.8 N.A. 78.9 N.A. N.A. 27.8 N.A. N.A. N.A. N.A. N.A. 47.7 N.A. N.A.
Protein Similarity: 100 N.A. N.A. 70.9 N.A. 87.5 N.A. N.A. 32.9 N.A. N.A. N.A. N.A. N.A. 60.2 N.A. N.A.
P-Site Identity: 100 N.A. N.A. 6.6 N.A. 6.6 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: 100 N.A. N.A. 26.6 N.A. 6.6 N.A. N.A. 0 N.A. N.A. N.A. N.A. N.A. 6.6 N.A. N.A.
Percent
Protein Identity: 32.1 31.8 N.A. 30.5 28.6 N.A.
Protein Similarity: 48.4 50.5 N.A. 48.4 50 N.A.
P-Site Identity: 26.6 20 N.A. 20 6.6 N.A.
P-Site Similarity: 33.3 20 N.A. 33.3 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 12 0 23 12 0 0 12 23 12 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 12 0 12 12 0 0 0 0 0 0 12 12 12 0 0 % D
% Glu: 34 0 12 0 12 0 0 0 0 0 12 0 23 23 12 % E
% Phe: 12 0 23 0 0 0 12 0 12 12 12 0 34 12 0 % F
% Gly: 0 23 0 0 0 12 12 0 0 0 0 0 12 0 0 % G
% His: 12 0 0 0 0 0 0 23 0 0 0 45 0 0 0 % H
% Ile: 0 23 0 12 0 12 0 0 0 23 0 0 0 12 12 % I
% Lys: 0 0 0 12 0 0 12 0 34 0 0 0 12 0 12 % K
% Leu: 0 23 0 0 12 12 23 0 12 12 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 12 12 0 12 0 0 12 0 % N
% Pro: 0 0 0 0 12 23 0 0 0 0 0 0 0 0 0 % P
% Gln: 12 0 0 12 12 0 0 0 0 0 12 0 0 23 12 % Q
% Arg: 0 12 0 0 0 0 0 0 0 0 12 12 0 0 23 % R
% Ser: 0 0 0 12 23 0 12 23 12 12 0 0 0 0 0 % S
% Thr: 0 0 0 0 12 0 12 0 0 23 23 12 0 12 0 % T
% Val: 0 12 12 23 0 12 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 23 0 0 0 12 0 12 0 0 0 % W
% Tyr: 0 0 12 0 12 0 0 12 0 0 0 0 0 0 23 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _