Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.

Updated: 2017 Aug. 1

| Home | Kinexus | Contact | Credits

Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A42 All Species: 36.67
Human Site: S178 Identified Species: 53.78
UniProt: Q86VD7 Number Species: 15
    Phosphosite Substitution
    Charge Score: -0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VD7 NP_848621.1 318 35409 S178 F H V F I R I S R E E G L K T
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115665 512 56385 S372 F H V F I R I S R E E G L K T
Dog Lupus familis XP_852174 318 35352 S178 F H V F I R I S R E E G L K T
Cat Felis silvestris
Mouse Mus musculus Q8R0Y8 318 35222 S178 F H V F I R I S R E E G L K T
Rat Rattus norvegicus P0C546 318 35081 S178 F H V F I R I S R E E G L K T
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512946 298 33296 T159 S R E E G L K T L Y R G F A P
Chicken Gallus gallus XP_424684 316 35193 S170 V H V F I R I S R E E G L K T
Frog Xenopus laevis Q5PQ27 327 36043 S181 I H V F M R M S R E E G L K S
Zebra Danio Brachydanio rerio Q0P483 321 35318 S180 M D V F V R I S R E E G L K T
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650891 365 40350 W216 R Q V F T K I W V E E G P R T
Honey Bee Apis mellifera XP_396993 338 37508 Y192 R Q I F V R I Y M E E G I A A
Nematode Worm Caenorhab. elegans Q19529 531 59257 Y388 F H F A H K M Y T K E G I K C
Sea Urchin Strong. purpuratus XP_781807 319 35365 L174 M S M F L M T L R I D G A S S
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609 L275 A H A F V K I L R D E G P S E
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798 L232 S Q V A L S M L R D E G I A S
Baker's Yeast Sacchar. cerevisiae Q12251 326 35895 R183 Q L L S E T Y R L E G G L R G
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 61.7 92.7 N.A. 92.1 90.8 N.A. 78.6 75.1 74.3 73.2 N.A. 49.8 48.2 21.2 56.4
Protein Similarity: 100 N.A. 61.7 94.9 N.A. 95.5 94.9 N.A. 85.5 85.8 85.3 83.1 N.A. 61.6 65.9 39.1 71.7
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 93.3 73.3 80 N.A. 46.6 40 33.3 20
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 13.3 93.3 93.3 86.6 N.A. 60 60 60 46.6
Percent
Protein Identity: N.A. 25.4 N.A. 32 34 N.A.
Protein Similarity: N.A. 41.9 N.A. 48 52.7 N.A.
P-Site Identity: N.A. 40 N.A. 26.6 20 N.A.
P-Site Similarity: N.A. 60 N.A. 60 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 7 13 0 0 0 0 0 0 0 0 7 19 7 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % C
% Asp: 0 7 0 0 0 0 0 0 0 13 7 0 0 0 0 % D
% Glu: 0 0 7 7 7 0 0 0 0 69 82 0 0 0 7 % E
% Phe: 38 0 7 75 0 0 0 0 0 0 0 0 7 0 0 % F
% Gly: 0 0 0 0 7 0 0 0 0 0 7 100 0 0 7 % G
% His: 0 57 0 0 7 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 7 0 7 0 38 0 63 0 0 7 0 0 19 0 0 % I
% Lys: 0 0 0 0 0 19 7 0 0 7 0 0 0 57 0 % K
% Leu: 0 7 7 0 13 7 0 19 13 0 0 0 57 0 0 % L
% Met: 13 0 7 0 7 7 19 0 7 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 13 0 7 % P
% Gln: 7 19 0 0 0 0 0 0 0 0 0 0 0 0 0 % Q
% Arg: 13 7 0 0 0 57 0 7 69 0 7 0 0 13 0 % R
% Ser: 13 7 0 7 0 7 0 50 0 0 0 0 0 13 19 % S
% Thr: 0 0 0 0 7 7 7 7 7 0 0 0 0 0 50 % T
% Val: 7 0 63 0 19 0 0 0 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 7 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 7 13 0 7 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _