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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A42 All Species: 38.48
Human Site: S219 Identified Species: 56.44
UniProt: Q86VD7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VD7 NP_848621.1 318 35409 S219 K S L H R E Y S G R R Q P Y P
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115665 512 56385 S413 K S L H R E Y S G R R Q P Y P
Dog Lupus familis XP_852174 318 35352 S219 K S L H R E Y S G R P Q P Y P
Cat Felis silvestris
Mouse Mus musculus Q8R0Y8 318 35222 S219 K S L H R E Y S G R P Q P Y P
Rat Rattus norvegicus P0C546 318 35081 S219 K S L H R E Y S G R P Q P Y P
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512946 298 33296 P200 S G R S Q P Y P F E R M F F G
Chicken Gallus gallus XP_424684 316 35193 S211 K K L H A D H S G K S Q P S P
Frog Xenopus laevis Q5PQ27 327 36043 S222 K K L H A E H S G R T Q P Y T
Zebra Danio Brachydanio rerio Q0P483 321 35318 T221 K K T H A E K T G R A H P F P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650891 365 40350 V257 K R E Y Y E V V G N N K P N T
Honey Bee Apis mellifera XP_396993 338 37508 T233 R N L L T V Y T V A I P G F S
Nematode Worm Caenorhab. elegans Q19529 531 59257 Y429 K S M Y T K Y Y T E H T E P G
Sea Urchin Strong. purpuratus XP_781807 319 35365 T215 K K Q H R E Y T N R K E P S P
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609 T316 K R L Y R R A T G R R P G A D
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798 Y273 K K S L P E E Y R K K A Q S S
Baker's Yeast Sacchar. cerevisiae Q12251 326 35895 S224 R E F G V N S S D A Q P S W K
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 61.7 92.7 N.A. 92.1 90.8 N.A. 78.6 75.1 74.3 73.2 N.A. 49.8 48.2 21.2 56.4
Protein Similarity: 100 N.A. 61.7 94.9 N.A. 95.5 94.9 N.A. 85.5 85.8 85.3 83.1 N.A. 61.6 65.9 39.1 71.7
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 13.3 53.3 66.6 46.6 N.A. 26.6 13.3 20 53.3
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 26.6 73.3 73.3 60 N.A. 40 40 40 73.3
Percent
Protein Identity: N.A. 25.4 N.A. 32 34 N.A.
Protein Similarity: N.A. 41.9 N.A. 48 52.7 N.A.
P-Site Identity: N.A. 40 N.A. 13.3 6.6 N.A.
P-Site Similarity: N.A. 53.3 N.A. 26.6 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 19 0 7 0 0 13 7 7 0 7 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 7 0 0 7 0 0 0 0 0 7 % D
% Glu: 0 7 7 0 0 63 7 0 0 13 0 7 7 0 0 % E
% Phe: 0 0 7 0 0 0 0 0 7 0 0 0 7 19 0 % F
% Gly: 0 7 0 7 0 0 0 0 63 0 0 0 13 0 13 % G
% His: 0 0 0 57 0 0 13 0 0 0 7 7 0 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % I
% Lys: 82 32 0 0 0 7 7 0 0 13 13 7 0 0 7 % K
% Leu: 0 0 57 13 0 0 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 7 0 0 0 7 0 0 7 7 7 0 0 7 0 % N
% Pro: 0 0 0 0 7 7 0 7 0 0 19 19 63 7 50 % P
% Gln: 0 0 7 0 7 0 0 0 0 0 7 44 7 0 0 % Q
% Arg: 13 13 7 0 44 7 0 0 7 57 25 0 0 0 0 % R
% Ser: 7 38 7 7 0 0 7 50 0 0 7 0 7 19 13 % S
% Thr: 0 0 7 0 13 0 0 25 7 0 7 7 0 0 13 % T
% Val: 0 0 0 0 7 7 7 7 7 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 7 0 % W
% Tyr: 0 0 0 19 7 0 57 13 0 0 0 0 0 38 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _