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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A42 All Species: 33.64
Human Site: Y114 Identified Species: 49.33
UniProt: Q86VD7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0.07
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VD7 NP_848621.1 318 35409 Y114 Q F S A H E E Y K R I L G S Y
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115665 512 56385 Y308 Q F S A H E E Y K R I L G S Y
Dog Lupus familis XP_852174 318 35352 Y114 Q F S A H E E Y K R I L G R Y
Cat Felis silvestris
Mouse Mus musculus Q8R0Y8 318 35222 Y114 Q F S A H E E Y K R I L G H Y
Rat Rattus norvegicus P0C546 318 35081 Y114 Q F S A H E E Y K R I L G H Y
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512946 298 33296 E101 R Y F G F Q G E A L P P W P R
Chicken Gallus gallus XP_424684 316 35193 Y106 Q F C A H E E Y K Q L L G S Y
Frog Xenopus laevis Q5PQ27 327 36043 Y117 Q F C A H E Q Y K K L L G S Y
Zebra Danio Brachydanio rerio Q0P483 321 35318 Y116 Q F C A H E Q Y K G I L G K Y
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650891 365 40350 W154 Q F T A H E Q W R R I L H V D
Honey Bee Apis mellifera XP_396993 338 37508 W131 Q F T A H E Q W K R I L G V N
Nematode Worm Caenorhab. elegans Q19529 531 59257 I325 K F M C Y D Q I K R W M Q E Y
Sea Urchin Strong. purpuratus XP_781807 319 35365 Y113 Q F A A H E Q Y K K L L N T H
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609 A213 E H F T Y D T A K K F L T P K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798 L168 L P Y S A V Q L L A Y E S Y K
Baker's Yeast Sacchar. cerevisiae Q12251 326 35895 C104 Q F V V Y E A C K K K L F H V
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 61.7 92.7 N.A. 92.1 90.8 N.A. 78.6 75.1 74.3 73.2 N.A. 49.8 48.2 21.2 56.4
Protein Similarity: 100 N.A. 61.7 94.9 N.A. 95.5 94.9 N.A. 85.5 85.8 85.3 83.1 N.A. 61.6 65.9 39.1 71.7
P-Site Identity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 0 80 73.3 73.3 N.A. 53.3 66.6 26.6 53.3
P-Site Similarity: 100 N.A. 100 93.3 N.A. 93.3 93.3 N.A. 20 93.3 93.3 80 N.A. 80 86.6 60 93.3
Percent
Protein Identity: N.A. 25.4 N.A. 32 34 N.A.
Protein Similarity: N.A. 41.9 N.A. 48 52.7 N.A.
P-Site Identity: N.A. 13.3 N.A. 0 33.3 N.A.
P-Site Similarity: N.A. 40 N.A. 13.3 46.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 7 69 7 0 7 7 7 7 0 0 0 0 0 % A
% Cys: 0 0 19 7 0 0 0 7 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 13 0 0 0 0 0 0 0 0 7 % D
% Glu: 7 0 0 0 0 75 38 7 0 0 0 7 0 7 0 % E
% Phe: 0 82 13 0 7 0 0 0 0 0 7 0 7 0 0 % F
% Gly: 0 0 0 7 0 0 7 0 0 7 0 0 57 0 0 % G
% His: 0 7 0 0 69 0 0 0 0 0 0 0 7 19 7 % H
% Ile: 0 0 0 0 0 0 0 7 0 0 50 0 0 0 0 % I
% Lys: 7 0 0 0 0 0 0 0 82 25 7 0 0 7 13 % K
% Leu: 7 0 0 0 0 0 0 7 7 7 19 82 0 0 0 % L
% Met: 0 0 7 0 0 0 0 0 0 0 0 7 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 7 0 7 % N
% Pro: 0 7 0 0 0 0 0 0 0 0 7 7 0 13 0 % P
% Gln: 75 0 0 0 0 7 44 0 0 7 0 0 7 0 0 % Q
% Arg: 7 0 0 0 0 0 0 0 7 50 0 0 0 7 7 % R
% Ser: 0 0 32 7 0 0 0 0 0 0 0 0 7 25 0 % S
% Thr: 0 0 13 7 0 0 7 0 0 0 0 0 7 7 0 % T
% Val: 0 0 7 7 0 7 0 0 0 0 0 0 0 13 7 % V
% Trp: 0 0 0 0 0 0 0 13 0 0 7 0 7 0 0 % W
% Tyr: 0 7 7 0 19 0 0 57 0 0 7 0 0 7 57 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _