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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A42
All Species:
30
Human Site:
Y122
Identified Species:
44
UniProt:
Q86VD7
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.13
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VD7
NP_848621.1
318
35409
Y122
K
R
I
L
G
S
Y
Y
G
F
R
G
E
A
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115665
512
56385
Y316
K
R
I
L
G
S
Y
Y
G
F
R
G
E
A
L
Dog
Lupus familis
XP_852174
318
35352
Y122
K
R
I
L
G
R
Y
Y
G
F
R
G
E
A
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0Y8
318
35222
Y122
K
R
I
L
G
H
Y
Y
G
F
R
G
E
A
L
Rat
Rattus norvegicus
P0C546
318
35081
Y122
K
R
I
L
G
H
Y
Y
G
F
R
G
E
A
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512946
298
33296
L109
A
L
P
P
W
P
R
L
L
A
G
A
L
A
G
Chicken
Gallus gallus
XP_424684
316
35193
Y114
K
Q
L
L
G
S
Y
Y
G
F
Q
G
K
A
L
Frog
Xenopus laevis
Q5PQ27
327
36043
Y125
K
K
L
L
G
S
Y
Y
G
F
Q
G
S
A
L
Zebra Danio
Brachydanio rerio
Q0P483
321
35318
Y124
K
G
I
L
G
K
Y
Y
G
F
Q
G
K
A
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650891
365
40350
K162
R
R
I
L
H
V
D
K
D
G
T
N
T
K
G
Honey Bee
Apis mellifera
XP_396993
338
37508
G139
K
R
I
L
G
V
N
G
S
E
R
E
K
P
G
Nematode Worm
Caenorhab. elegans
Q19529
531
59257
K333
K
R
W
M
Q
E
Y
K
G
G
A
E
L
S
T
Sea Urchin
Strong. purpuratus
XP_781807
319
35365
N121
K
K
L
L
N
T
H
N
T
Q
N
L
N
P
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P29518
436
46609
G221
K
K
F
L
T
P
K
G
D
E
P
P
K
I
P
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65023
381
41798
N176
L
A
Y
E
S
Y
K
N
L
F
K
G
K
D
D
Baker's Yeast
Sacchar. cerevisiae
Q12251
326
35895
N112
K
K
K
L
F
H
V
N
G
N
N
G
Q
E
Q
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
61.7
92.7
N.A.
92.1
90.8
N.A.
78.6
75.1
74.3
73.2
N.A.
49.8
48.2
21.2
56.4
Protein Similarity:
100
N.A.
61.7
94.9
N.A.
95.5
94.9
N.A.
85.5
85.8
85.3
83.1
N.A.
61.6
65.9
39.1
71.7
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
6.6
73.3
73.3
73.3
N.A.
20
40
26.6
13.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
6.6
100
93.3
86.6
N.A.
26.6
46.6
40
40
Percent
Protein Identity:
N.A.
25.4
N.A.
32
34
N.A.
Protein Similarity:
N.A.
41.9
N.A.
48
52.7
N.A.
P-Site Identity:
N.A.
13.3
N.A.
13.3
26.6
N.A.
P-Site Similarity:
N.A.
26.6
N.A.
26.6
40
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
7
7
0
0
0
0
0
0
0
7
7
7
0
57
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
13
0
0
0
0
7
7
% D
% Glu:
0
0
0
7
0
7
0
0
0
13
0
13
32
7
0
% E
% Phe:
0
0
7
0
7
0
0
0
0
57
0
0
0
0
0
% F
% Gly:
0
7
0
0
57
0
0
13
63
13
7
63
0
0
19
% G
% His:
0
0
0
0
7
19
7
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
50
0
0
0
0
0
0
0
0
0
0
7
0
% I
% Lys:
82
25
7
0
0
7
13
13
0
0
7
0
32
7
0
% K
% Leu:
7
7
19
82
0
0
0
7
13
0
0
7
13
0
50
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
7
0
7
19
0
7
13
7
7
0
0
% N
% Pro:
0
0
7
7
0
13
0
0
0
0
7
7
0
13
7
% P
% Gln:
0
7
0
0
7
0
0
0
0
7
19
0
7
0
7
% Q
% Arg:
7
50
0
0
0
7
7
0
0
0
38
0
0
0
0
% R
% Ser:
0
0
0
0
7
25
0
0
7
0
0
0
7
7
0
% S
% Thr:
0
0
0
0
7
7
0
0
7
0
7
0
7
0
7
% T
% Val:
0
0
0
0
0
13
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
7
0
7
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
7
0
0
7
57
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _