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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
SLC25A42
All Species:
27.58
Human Site:
Y218
Identified Species:
40.44
UniProt:
Q86VD7
Number Species:
15
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VD7
NP_848621.1
318
35409
Y218
L
K
S
L
H
R
E
Y
S
G
R
R
Q
P
Y
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001115665
512
56385
Y412
L
K
S
L
H
R
E
Y
S
G
R
R
Q
P
Y
Dog
Lupus familis
XP_852174
318
35352
Y218
L
K
S
L
H
R
E
Y
S
G
R
P
Q
P
Y
Cat
Felis silvestris
Mouse
Mus musculus
Q8R0Y8
318
35222
Y218
L
K
S
L
H
R
E
Y
S
G
R
P
Q
P
Y
Rat
Rattus norvegicus
P0C546
318
35081
Y218
L
K
S
L
H
R
E
Y
S
G
R
P
Q
P
Y
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512946
298
33296
Y199
H
S
G
R
S
Q
P
Y
P
F
E
R
M
F
F
Chicken
Gallus gallus
XP_424684
316
35193
H210
L
K
K
L
H
A
D
H
S
G
K
S
Q
P
S
Frog
Xenopus laevis
Q5PQ27
327
36043
H221
L
K
K
L
H
A
E
H
S
G
R
T
Q
P
Y
Zebra Danio
Brachydanio rerio
Q0P483
321
35318
K220
L
K
K
T
H
A
E
K
T
G
R
A
H
P
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_650891
365
40350
V256
L
K
R
E
Y
Y
E
V
V
G
N
N
K
P
N
Honey Bee
Apis mellifera
XP_396993
338
37508
Y232
L
R
N
L
L
T
V
Y
T
V
A
I
P
G
F
Nematode Worm
Caenorhab. elegans
Q19529
531
59257
Y428
L
K
S
M
Y
T
K
Y
Y
T
E
H
T
E
P
Sea Urchin
Strong. purpuratus
XP_781807
319
35365
Y214
L
K
K
Q
H
R
E
Y
T
N
R
K
E
P
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
P29518
436
46609
A315
L
K
R
L
Y
R
R
A
T
G
R
R
P
G
A
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
O65023
381
41798
E272
V
K
K
S
L
P
E
E
Y
R
K
K
A
Q
S
Baker's Yeast
Sacchar. cerevisiae
Q12251
326
35895
S223
L
R
E
F
G
V
N
S
S
D
A
Q
P
S
W
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
61.7
92.7
N.A.
92.1
90.8
N.A.
78.6
75.1
74.3
73.2
N.A.
49.8
48.2
21.2
56.4
Protein Similarity:
100
N.A.
61.7
94.9
N.A.
95.5
94.9
N.A.
85.5
85.8
85.3
83.1
N.A.
61.6
65.9
39.1
71.7
P-Site Identity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
13.3
53.3
73.3
46.6
N.A.
33.3
20
26.6
53.3
P-Site Similarity:
100
N.A.
100
93.3
N.A.
93.3
93.3
N.A.
26.6
73.3
80
60
N.A.
46.6
46.6
46.6
73.3
Percent
Protein Identity:
N.A.
25.4
N.A.
32
34
N.A.
Protein Similarity:
N.A.
41.9
N.A.
48
52.7
N.A.
P-Site Identity:
N.A.
46.6
N.A.
13.3
13.3
N.A.
P-Site Similarity:
N.A.
60
N.A.
33.3
33.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
19
0
7
0
0
13
7
7
0
7
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
7
0
0
7
0
0
0
0
0
% D
% Glu:
0
0
7
7
0
0
63
7
0
0
13
0
7
7
0
% E
% Phe:
0
0
0
7
0
0
0
0
0
7
0
0
0
7
19
% F
% Gly:
0
0
7
0
7
0
0
0
0
63
0
0
0
13
0
% G
% His:
7
0
0
0
57
0
0
13
0
0
0
7
7
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
7
0
0
0
% I
% Lys:
0
82
32
0
0
0
7
7
0
0
13
13
7
0
0
% K
% Leu:
88
0
0
57
13
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
7
0
0
0
0
0
0
0
0
7
0
0
% M
% Asn:
0
0
7
0
0
0
7
0
0
7
7
7
0
0
7
% N
% Pro:
0
0
0
0
0
7
7
0
7
0
0
19
19
63
7
% P
% Gln:
0
0
0
7
0
7
0
0
0
0
0
7
44
7
0
% Q
% Arg:
0
13
13
7
0
44
7
0
0
7
57
25
0
0
0
% R
% Ser:
0
7
38
7
7
0
0
7
50
0
0
7
0
7
19
% S
% Thr:
0
0
0
7
0
13
0
0
25
7
0
7
7
0
0
% T
% Val:
7
0
0
0
0
7
7
7
7
7
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
7
% W
% Tyr:
0
0
0
0
19
7
0
57
13
0
0
0
0
0
38
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _