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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SLC25A42 All Species: 44.24
Human Site: Y245 Identified Species: 64.89
UniProt: Q86VD7 Number Species: 15
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VD7 NP_848621.1 318 35409 Y245 L I G Q S A S Y P L D V V R R
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001115665 512 56385 Y439 L I G Q S A S Y P L D V V R R
Dog Lupus familis XP_852174 318 35352 Y245 L I G Q S A S Y P L D V V R R
Cat Felis silvestris
Mouse Mus musculus Q8R0Y8 318 35222 Y245 L I G Q S A S Y P L D V V R R
Rat Rattus norvegicus P0C546 318 35081 Y245 L I G Q S A S Y P L D V V R R
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512946 298 33296 R226 Y P L D V V R R R M Q T A G V
Chicken Gallus gallus XP_424684 316 35193 Y237 L I G Q S A S Y P L D V V R R
Frog Xenopus laevis Q5PQ27 327 36043 Y248 L F G Q S S S Y P L D V V R R
Zebra Danio Brachydanio rerio Q0P483 321 35318 Y247 L I G Q S A S Y P L D V V R R
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_650891 365 40350 D286 Q T A S Y P L D I V R R R M Q
Honey Bee Apis mellifera XP_396993 338 37508 Y258 M V A Q T S S Y P L D I I R R
Nematode Worm Caenorhab. elegans Q19529 531 59257 L458 G Q L A S Y P L A L V R T R L
Sea Urchin Strong. purpuratus XP_781807 319 35365 Y241 L F G Q S A S Y P L D V I R R
Poplar Tree Populus trichocarpa
Maize Zea mays P29518 436 46609 F345 A I A S S A T F P L E V A R K
Rice Oryza sativa
Thale Cress Arabidopsis thaliana O65023 381 41798 T300 L T C Y P L D T V R R Q M Q M
Baker's Yeast Sacchar. cerevisiae Q12251 326 35895 Y252 G V A Q T I T Y P F D L L R R
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 61.7 92.7 N.A. 92.1 90.8 N.A. 78.6 75.1 74.3 73.2 N.A. 49.8 48.2 21.2 56.4
Protein Similarity: 100 N.A. 61.7 94.9 N.A. 95.5 94.9 N.A. 85.5 85.8 85.3 83.1 N.A. 61.6 65.9 39.1 71.7
P-Site Identity: 100 N.A. 100 100 N.A. 100 100 N.A. 0 100 86.6 100 N.A. 0 53.3 20 86.6
P-Site Similarity: 100 N.A. 100 100 N.A. 100 100 N.A. 6.6 100 93.3 100 N.A. 13.3 93.3 20 93.3
Percent
Protein Identity: N.A. 25.4 N.A. 32 34 N.A.
Protein Similarity: N.A. 41.9 N.A. 48 52.7 N.A.
P-Site Identity: N.A. 46.6 N.A. 6.6 40 N.A.
P-Site Similarity: N.A. 73.3 N.A. 20 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 7 0 25 7 0 57 0 0 7 0 0 0 13 0 0 % A
% Cys: 0 0 7 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 7 0 0 7 7 0 0 69 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 7 0 0 0 0 % E
% Phe: 0 13 0 0 0 0 0 7 0 7 0 0 0 0 0 % F
% Gly: 13 0 57 0 0 0 0 0 0 0 0 0 0 7 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 50 0 0 0 7 0 0 7 0 0 7 13 0 0 % I
% Lys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 7 % K
% Leu: 63 0 13 0 0 7 7 7 0 75 0 7 7 0 7 % L
% Met: 7 0 0 0 0 0 0 0 0 7 0 0 7 7 7 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 7 0 0 7 7 7 0 75 0 0 0 0 0 0 % P
% Gln: 7 7 0 69 0 0 0 0 0 0 7 7 0 7 7 % Q
% Arg: 0 0 0 0 0 0 7 7 7 7 13 13 7 82 69 % R
% Ser: 0 0 0 13 69 13 63 0 0 0 0 0 0 0 0 % S
% Thr: 0 13 0 0 13 0 13 7 0 0 0 7 7 0 0 % T
% Val: 0 13 0 0 7 7 0 0 7 7 7 63 50 0 7 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 7 0 0 7 7 7 0 69 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _