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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: PIGZ All Species: 4.85
Human Site: S361 Identified Species: 9.7
UniProt: Q86VD9 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VD9 NP_079439.2 579 63473 S361 L R A L G A R S L L S S P R S
Chimpanzee Pan troglodytes
Rhesus Macaque Macaca mulatta XP_001096610 446 48480 A258 H A P V L P S A P T H Y T L L
Dog Lupus familis XP_545157 592 64399 S361 L R A P G G W S L L S S P R P
Cat Felis silvestris
Mouse Mus musculus Q8BTP0 560 62025 G333 S R V R G A R G L L S S S K S
Rat Rattus norvegicus XP_002724776 558 61646 G331 L G E P G T Q G L L S S S K S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001512679 710 75710 P470 A R P G A P R P P P R Q P H A
Chicken Gallus gallus XP_426699 559 62255 S344 Y R G S P R L S V P S D G Q P
Frog Xenopus laevis
Zebra Danio Brachydanio rerio Q7SXZ1 536 62222 R343 L L A H K E F R F I Y P V L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q8MT80 696 80199 P376 R A E Y Q V L P R F Q S I V S
Honey Bee Apis mellifera XP_624036 592 68391 P383 K A R W L N L P R I Q S V V G
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001204359 586 65351 F348 E P Q S G K T F S T S T S R A
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q04174 516 59882 P324 R F L V P L V P L L V T N L N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 N.A. 61.3 77.8 N.A. 75.9 75.6 N.A. 51.9 48.8 N.A. 21.4 N.A. 26.8 25.5 N.A. 28.5
Protein Similarity: 100 N.A. 62.5 82.9 N.A. 82.2 82.3 N.A. 59.2 62.3 N.A. 34.3 N.A. 39.6 44.5 N.A. 47.2
P-Site Identity: 100 N.A. 0 73.3 N.A. 60 46.6 N.A. 20 20 N.A. 13.3 N.A. 13.3 6.6 N.A. 20
P-Site Similarity: 100 N.A. 13.3 73.3 N.A. 66.6 60 N.A. 26.6 33.3 N.A. 20 N.A. 13.3 13.3 N.A. 33.3
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.3 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 39.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 13.3 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 33.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 9 25 25 0 9 17 0 9 0 0 0 0 0 0 17 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 0 0 9 0 0 0 % D
% Glu: 9 0 17 0 0 9 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 9 0 0 0 0 9 9 9 9 0 0 0 0 0 % F
% Gly: 0 9 9 9 42 9 0 17 0 0 0 0 9 0 9 % G
% His: 9 0 0 9 0 0 0 0 0 0 9 0 0 9 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 17 0 0 9 0 0 % I
% Lys: 9 0 0 0 9 9 0 0 0 0 0 0 0 17 0 % K
% Leu: 34 9 9 9 17 9 25 0 42 42 0 0 0 25 9 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 9 0 0 0 0 0 0 9 0 9 % N
% Pro: 0 9 17 17 17 17 0 34 17 17 0 9 25 0 25 % P
% Gln: 0 0 9 0 9 0 9 0 0 0 17 9 0 9 0 % Q
% Arg: 17 42 9 9 0 9 25 9 17 0 9 0 0 25 0 % R
% Ser: 9 0 0 17 0 0 9 25 9 0 50 50 25 0 34 % S
% Thr: 0 0 0 0 0 9 9 0 0 17 0 17 9 0 0 % T
% Val: 0 0 9 17 0 9 9 0 9 0 9 0 17 17 0 % V
% Trp: 0 0 0 9 0 0 9 0 0 0 0 0 0 0 0 % W
% Tyr: 9 0 0 9 0 0 0 0 0 0 9 9 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _