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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SERINC5 All Species: 25.15
Human Site: Y345 Identified Species: 55.33
UniProt: Q86VE9 Number Species: 10
    Phosphosite Substitution
    Charge Score: -0.1
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VE9 NP_840060.1 423 47009 Y345 S D A L Q G R Y A A P E L E I
Chimpanzee Pan troglodytes XP_001136963 461 51287 Y345 S D A L Q G R Y A A P E L E I
Rhesus Macaque Macaca mulatta XP_001109947 461 51236 Y345 S D A L Q G R Y A A P E L E I
Dog Lupus familis XP_536311 461 51188 Y345 S D A L Q G R Y A A P E L E V
Cat Felis silvestris
Mouse Mus musculus Q8BHJ6 461 51812 Y346 S D A L Q S R Y G A P E L E V
Rat Rattus norvegicus Q63175 460 51837 Y344 S D A L Q R R Y G A P E L E V
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507769 514 56779 L404 N N S Q V N K L T L T S D E S
Chicken Gallus gallus XP_424762 462 51593 Y345 S E T L R G I Y A A P E T E V
Frog Xenopus laevis NP_001090209 460 50837 L353 S Q V N K L T L T S D E S T L
Zebra Danio Brachydanio rerio Q803X0 460 51965 R345 S A A L Q V Y R N D M P E N E
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae Q12116 473 52212 G341 G N D I E Y E G L G G Q T R N
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 90.4 86.5 81.3 N.A. 74.6 75 N.A. 34 68.8 32.3 57.1 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 91.1 88 87.4 N.A. 82.6 81.3 N.A. 49.2 79.4 49.3 70.2 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 93.3 N.A. 80 80 N.A. 6.6 60 13.3 26.6 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 100 N.A. 86.6 86.6 N.A. 33.3 80 33.3 26.6 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. 23.4 N.A.
Protein Similarity: N.A. N.A. N.A. N.A. 42.2 N.A.
P-Site Identity: N.A. N.A. N.A. N.A. 0 N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. 26.6 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 10 64 0 0 0 0 0 46 64 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 55 10 0 0 0 0 0 0 10 10 0 10 0 0 % D
% Glu: 0 10 0 0 10 0 10 0 0 0 0 73 10 73 10 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 10 0 0 0 0 46 0 10 19 10 10 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 10 0 0 10 0 0 0 0 0 0 0 28 % I
% Lys: 0 0 0 0 10 0 10 0 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 73 0 10 0 19 10 10 0 0 55 0 10 % L
% Met: 0 0 0 0 0 0 0 0 0 0 10 0 0 0 0 % M
% Asn: 10 19 0 10 0 10 0 0 10 0 0 0 0 10 10 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 64 10 0 0 0 % P
% Gln: 0 10 0 10 64 0 0 0 0 0 0 10 0 0 0 % Q
% Arg: 0 0 0 0 10 10 55 10 0 0 0 0 0 10 0 % R
% Ser: 82 0 10 0 0 10 0 0 0 10 0 10 10 0 10 % S
% Thr: 0 0 10 0 0 0 10 0 19 0 10 0 19 10 0 % T
% Val: 0 0 10 0 10 10 0 0 0 0 0 0 0 0 37 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 10 10 64 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _