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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: IGFN1 All Species: 11.52
Human Site: T954 Identified Species: 42.22
UniProt: Q86VF2 Number Species: 6
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VF2 NP_001158058 1251 137763 T954 K F L V D S S T K D L L T V K
Chimpanzee Pan troglodytes XP_514089 1692 184202 T1395 K F L V D S S T K D L L T V K
Rhesus Macaque Macaca mulatta XP_001098956 863 93226 D576 L L T V K V G D T V R V P I S
Dog Lupus familis XP_547363 1264 134588 T955 K F L M D S G T K D S R M V R
Cat Felis silvestris
Mouse Mus musculus Q3KNY0 1267 139421 T970 R F L M D S G T K D T L M V R
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518110 389 44649 L102 P G S K E H I L Q G P T G L L
Chicken Gallus gallus P16419 1132 126924 R845 L R Q T Y I R R V G E Q V N L
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 72.4 64.9 51.7 N.A. 76.6 N.A. N.A. 23.1 23.7 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 72.8 66.6 61.3 N.A. 85.3 N.A. N.A. 26.2 39.4 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 6.6 60 N.A. 60 N.A. N.A. 0 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 20 73.3 N.A. 80 N.A. N.A. 20 0 N.A. N.A. N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 58 0 0 15 0 58 0 0 0 0 0 % D
% Glu: 0 0 0 0 15 0 0 0 0 0 15 0 0 0 0 % E
% Phe: 0 58 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 0 0 0 43 0 0 29 0 0 15 0 0 % G
% His: 0 0 0 0 0 15 0 0 0 0 0 0 0 0 0 % H
% Ile: 0 0 0 0 0 15 15 0 0 0 0 0 0 15 0 % I
% Lys: 43 0 0 15 15 0 0 0 58 0 0 0 0 0 29 % K
% Leu: 29 15 58 0 0 0 0 15 0 0 29 43 0 15 29 % L
% Met: 0 0 0 29 0 0 0 0 0 0 0 0 29 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 0 0 15 0 % N
% Pro: 15 0 0 0 0 0 0 0 0 0 15 0 15 0 0 % P
% Gln: 0 0 15 0 0 0 0 0 15 0 0 15 0 0 0 % Q
% Arg: 15 15 0 0 0 0 15 15 0 0 15 15 0 0 29 % R
% Ser: 0 0 15 0 0 58 29 0 0 0 15 0 0 0 15 % S
% Thr: 0 0 15 15 0 0 0 58 15 0 15 15 29 0 0 % T
% Val: 0 0 0 43 0 15 0 0 15 15 0 15 15 58 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 15 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _