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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF27 All Species: 21.82
Human Site: S558 Identified Species: 36.92
UniProt: Q86VH2 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VH2 NP_060046.1 1401 160283 S558 E L T K L N L S V T S S A K E
Chimpanzee Pan troglodytes XP_520097 1402 160381 S558 E L T K L N L S V T S S A K E
Rhesus Macaque Macaca mulatta XP_001103240 1325 151948 S482 E L T K L N L S V T S S A K E
Dog Lupus familis XP_541265 1396 159580 S558 E L T K L N L S M T S S A T E
Cat Felis silvestris
Mouse Mus musculus Q7M6Z4 1394 158937 S558 E L A K R S L S V P T S A K E
Rat Rattus norvegicus Q7M6Z5 1394 158861 S558 E L A K R S S S M P T S T K E
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518145 523 57911
Chicken Gallus gallus Q90640 1225 138905 Q508 A G E A E T G Q V T K R S S D
Frog Xenopus laevis Q91784 1226 138905 P501 E A A S F P V P E E D S G E K
Zebra Danio Brachydanio rerio Q58G59 1363 154819 L546 Q Q D L I A E L H S L L A Q P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395595 1064 123475 S366 V D H E I K I S C P I E H Q E
Nematode Worm Caenorhab. elegans P46873 699 78760
Sea Urchin Strong. purpuratus P46871 742 84184 N44 R G L V E V T N P K G P P G E
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 N358 D Y A H R A K N I R N K P E V
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 90.3 85.9 N.A. 78.6 78 N.A. 20 26.3 26.4 42.3 N.A. N.A. 27.3 26 24.7
Protein Similarity: 100 99.3 92.5 91.7 N.A. 88.3 89 N.A. 28.3 45.4 46.7 61.9 N.A. N.A. 46.7 36 37.6
P-Site Identity: 100 100 100 86.6 N.A. 66.6 46.6 N.A. 0 13.3 13.3 6.6 N.A. N.A. 13.3 0 6.6
P-Site Similarity: 100 100 100 93.3 N.A. 80 66.6 N.A. 0 26.6 33.3 33.3 N.A. N.A. 40 0 13.3
Percent
Protein Identity: N.A. N.A. N.A. 24.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 0 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 33.3 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 8 29 8 0 15 0 0 0 0 0 0 43 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 8 0 0 0 0 0 0 % C
% Asp: 8 8 8 0 0 0 0 0 0 0 8 0 0 0 8 % D
% Glu: 50 0 8 8 15 0 8 0 8 8 0 8 0 15 58 % E
% Phe: 0 0 0 0 8 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 15 0 0 0 0 8 0 0 0 8 0 8 8 0 % G
% His: 0 0 8 8 0 0 0 0 8 0 0 0 8 0 0 % H
% Ile: 0 0 0 0 15 0 8 0 8 0 8 0 0 0 0 % I
% Lys: 0 0 0 43 0 8 8 0 0 8 8 8 0 36 8 % K
% Leu: 0 43 8 8 29 0 36 8 0 0 8 8 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 15 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 29 0 15 0 0 8 0 0 0 0 % N
% Pro: 0 0 0 0 0 8 0 8 8 22 0 8 15 0 8 % P
% Gln: 8 8 0 0 0 0 0 8 0 0 0 0 0 15 0 % Q
% Arg: 8 0 0 0 22 0 0 0 0 8 0 8 0 0 0 % R
% Ser: 0 0 0 8 0 15 8 50 0 8 29 50 8 8 0 % S
% Thr: 0 0 29 0 0 8 8 0 0 36 15 0 8 8 0 % T
% Val: 8 0 0 8 0 8 8 0 36 0 0 0 0 0 8 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 8 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _