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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KIF27 All Species: 14.24
Human Site: S601 Identified Species: 24.1
UniProt: Q86VH2 Number Species: 13
    Phosphosite Substitution
    Charge Score: -0.15
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86VH2 NP_060046.1 1401 160283 S601 Y I P S R Q D S R K V H T S P
Chimpanzee Pan troglodytes XP_520097 1402 160381 S601 Y I P S R Q D S R K V H T S P
Rhesus Macaque Macaca mulatta XP_001103240 1325 151948 S525 Y I P S R Q D S R K V H T S P
Dog Lupus familis XP_541265 1396 159580 S601 Y N P A R S D S R K V Y T S P
Cat Felis silvestris
Mouse Mus musculus Q7M6Z4 1394 158937 F601 Y I P S R Q D F K K V C S S T
Rat Rattus norvegicus Q7M6Z5 1394 158861 F601 Y I P S R Q D F K K V C S S S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001518145 523 57911
Chicken Gallus gallus Q90640 1225 138905 K547 A L K E A L A K K M I Q N D S
Frog Xenopus laevis Q91784 1226 138905 A541 K A L V M K E A L A K K M A Q
Zebra Danio Brachydanio rerio Q58G59 1363 154819 S586 R L T P P C D S D V G R S L A
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_395595 1064 123475 R405 E A V T M H E R A E L A E Q A
Nematode Worm Caenorhab. elegans P46873 699 78760 A40 V G Q V N L N A P D G A A K D
Sea Urchin Strong. purpuratus P46871 742 84184 V83 F R S L V E S V L Q G F N G T
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P82266 1056 119250 G397 Y A S R E K N G V Y M P K E R
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 98.8 90.3 85.9 N.A. 78.6 78 N.A. 20 26.3 26.4 42.3 N.A. N.A. 27.3 26 24.7
Protein Similarity: 100 99.3 92.5 91.7 N.A. 88.3 89 N.A. 28.3 45.4 46.7 61.9 N.A. N.A. 46.7 36 37.6
P-Site Identity: 100 100 100 73.3 N.A. 66.6 66.6 N.A. 0 0 0 13.3 N.A. N.A. 0 0 0
P-Site Similarity: 100 100 100 86.6 N.A. 80 80 N.A. 0 20 26.6 26.6 N.A. N.A. 26.6 13.3 20
Percent
Protein Identity: N.A. N.A. N.A. 24.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 43.7 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 6.6 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 8 22 0 8 8 0 8 15 8 8 0 15 8 8 15 % A
% Cys: 0 0 0 0 0 8 0 0 0 0 0 15 0 0 0 % C
% Asp: 0 0 0 0 0 0 50 0 8 8 0 0 0 8 8 % D
% Glu: 8 0 0 8 8 8 15 0 0 8 0 0 8 8 0 % E
% Phe: 8 0 0 0 0 0 0 15 0 0 0 8 0 0 0 % F
% Gly: 0 8 0 0 0 0 0 8 0 0 22 0 0 8 0 % G
% His: 0 0 0 0 0 8 0 0 0 0 0 22 0 0 0 % H
% Ile: 0 36 0 0 0 0 0 0 0 0 8 0 0 0 0 % I
% Lys: 8 0 8 0 0 15 0 8 22 43 8 8 8 8 0 % K
% Leu: 0 15 8 8 0 15 0 0 15 0 8 0 0 8 0 % L
% Met: 0 0 0 0 15 0 0 0 0 8 8 0 8 0 0 % M
% Asn: 0 8 0 0 8 0 15 0 0 0 0 0 15 0 0 % N
% Pro: 0 0 43 8 8 0 0 0 8 0 0 8 0 0 29 % P
% Gln: 0 0 8 0 0 36 0 0 0 8 0 8 0 8 8 % Q
% Arg: 8 8 0 8 43 0 0 8 29 0 0 8 0 0 8 % R
% Ser: 0 0 15 36 0 8 8 36 0 0 0 0 22 43 15 % S
% Thr: 0 0 8 8 0 0 0 0 0 0 0 0 29 0 15 % T
% Val: 8 0 8 15 8 0 0 8 8 8 43 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 50 0 0 0 0 0 0 0 0 8 0 8 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _