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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
IQGAP3
All Species:
4.85
Human Site:
S1509
Identified Species:
17.78
UniProt:
Q86VI3
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.33
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q86VI3
NP_839943.2
1631
184699
S1509
E
E
Q
G
D
Y
Y
S
Q
Y
I
R
A
C
L
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_547533
1692
191049
S1570
E
E
Q
G
D
Y
Y
S
Q
Y
I
R
T
C
L
Cat
Felis silvestris
Mouse
Mus musculus
Q9JKF1
1657
188738
K1528
G
E
Q
V
D
Y
Y
K
S
Y
I
K
T
C
L
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509899
540
60910
S456
L
M
K
L
K
A
Q
S
Y
S
Q
N
N
E
F
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082590
1618
184741
K1489
E
E
Q
V
D
Y
Y
K
S
Y
I
K
T
C
M
Zebra Danio
Brachydanio rerio
XP_001920847
855
96845
V771
A
R
L
H
E
K
G
V
L
I
D
I
D
D
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_001203784
771
87814
I687
I
I
A
T
V
D
M
I
P
Y
G
I
R
Y
I
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
N.A.
82.6
N.A.
58.7
N.A.
N.A.
22
N.A.
56.9
29.7
N.A.
N.A.
N.A.
N.A.
24.8
Protein Similarity:
100
N.A.
N.A.
89.4
N.A.
75.1
N.A.
N.A.
28
N.A.
74.1
40.5
N.A.
N.A.
N.A.
N.A.
36.2
P-Site Identity:
100
N.A.
N.A.
93.3
N.A.
60
N.A.
N.A.
6.6
N.A.
60
6.6
N.A.
N.A.
N.A.
N.A.
6.6
P-Site Similarity:
100
N.A.
N.A.
93.3
N.A.
66.6
N.A.
N.A.
13.3
N.A.
73.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
15
0
15
0
0
15
0
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
58
0
% C
% Asp:
0
0
0
0
58
15
0
0
0
0
15
0
15
15
0
% D
% Glu:
43
58
0
0
15
0
0
0
0
0
0
0
0
15
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
15
% F
% Gly:
15
0
0
29
0
0
15
0
0
0
15
0
0
0
0
% G
% His:
0
0
0
15
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
15
15
0
0
0
0
0
15
0
15
58
29
0
0
15
% I
% Lys:
0
0
15
0
15
15
0
29
0
0
0
29
0
0
0
% K
% Leu:
15
0
15
15
0
0
0
0
15
0
0
0
0
0
58
% L
% Met:
0
15
0
0
0
0
15
0
0
0
0
0
0
0
15
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
15
15
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
15
0
0
0
0
0
0
% P
% Gln:
0
0
58
0
0
0
15
0
29
0
15
0
0
0
0
% Q
% Arg:
0
15
0
0
0
0
0
0
0
0
0
29
15
0
0
% R
% Ser:
0
0
0
0
0
0
0
43
29
15
0
0
0
0
0
% S
% Thr:
0
0
0
15
0
0
0
0
0
0
0
0
43
0
0
% T
% Val:
0
0
0
29
15
0
0
15
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
58
58
0
15
72
0
0
0
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _